{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T18:43:37Z","timestamp":1786214617360,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Unintentional injuries are a major cause of death worldwide. Modern trauma systems have reduced morbidity and mortality through rapid prehospital care, yet trauma research faces challenges obtaining informed consent during emergencies. Because patients are often incapacitated and substitute decision makers are unavailable, studies commonly rely on deferred or waived consent. Despite their use, little is known about public perspectives on these models or on prehospital interventions such as paramedic\u2010administered blood transfusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore Canadian public perspectives on trauma research, alternative consent models, and prehospital blood transfusion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A multi\u2010methods community engagement study, including a national survey and 96 in situ interviews in four rural Ontario communities. Survey and interview questions assessed trust in healthcare, views on research consent, and acceptance of prehospital blood transfusion. Quantitative data were summarized descriptively; qualitative data underwent thematic analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Survey respondents reported strong trust in the healthcare system (75%) and support for clinical trials (80%). Acceptance of alternative consent was mixed, with only 40% finding it acceptable. Most agreed that data collected before withdrawal of consent should remain usable. Support for paramedic\u2010administered blood transfusion was high (70%), grounded in urgency and trust in paramedic expertise, though concerns included safety and autonomy. Interviews reinforced these themes, emphasizing conditional acceptance of deferred consent, preference for timely communication, and strong trust in paramedics during life\u2010threatening emergencies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Canadians support prehospital blood transfusion and recognize the need for trauma research, but acceptance of alternative consent models depends on transparency, perceived necessity, and respect for autonomy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.70250","type":"journal-article","created":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T06:23:23Z","timestamp":1777962203000},"page":"1480-1494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Understanding public perspectives of prehospital trauma research: A qualitative community engagement study on consent and blood transfusion"],"prefix":"10.1111","volume":"66","author":[{"given":"Katie N.","family":"Dainty","sequence":"first","affiliation":[{"name":"North York General Hospital  Toronto Canada"},{"name":"Institute of Health Policy, Management and Evaluation University of Toronto  Toronto Canada"},{"name":"FIRST60, Li Ka Shing Knowledge Institute St. Michael's Hospital  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Bianca","family":"Seaton","sequence":"additional","affiliation":[{"name":"North York General Hospital  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krystle","family":"Amog","sequence":"additional","affiliation":[{"name":"Institute of Health Policy, Management and Evaluation University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"McGowan","sequence":"additional","affiliation":[{"name":"FIRST60, Li Ka Shing Knowledge Institute St. Michael's Hospital  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2872-0643","authenticated-orcid":false,"given":"Brodie","family":"Nolan","sequence":"additional","affiliation":[{"name":"Institute of Health Policy, Management and Evaluation University of Toronto  Toronto Canada"},{"name":"FIRST60, Li Ka Shing Knowledge Institute St. Michael's Hospital  Toronto Canada"},{"name":"Department of Emergency Medicine St. Michael's Hospital, Unity Health Toronto  Toronto Canada"},{"name":"Temerty School of Medicine, Division of Emergency Medicine, Department of Medicine University of Toronto  Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the SWiFT Canada Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2010.08.014"},{"key":"e_1_2_11_3_1","unstructured":"Parachute.The cost of injury in Canada [Internet].https:\/\/parachute.ca\/en\/professional-resource\/cost-of-injury-in-canada\/. Accessed 10 Feb 2025"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e318252510a"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2005.09.027"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa052049"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.TA.0000061107.55798.31"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.02.006"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12910-019-0347-0"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0b013e318165c15c"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/08998280.2013.11928934"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-026-09592-9"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resplu.2024.100565"},{"key":"e_1_2_11_14_1","unstructured":"SwiFT Canada.Study of whole blood in frontline trauma.https:\/\/first60.ca\/current-studies\/swift\/. Accessed 27 Mar 2026"},{"key":"e_1_2_11_15_1","unstructured":"Statistics Canada.Population estimates quarterly.https:\/\/www150.statcan.gc.ca\/t1\/tbl1\/en\/tv.action?pid=1710000901. Accessed 27 Mar 2026"},{"key":"e_1_2_11_16_1","unstructured":"Ontario Paramedic Association.Ontario Paramedic Association Chapters.https:\/\/www.ontarioparamedic.ca\/about-us\/links\/. Accessed 27 Mar 2026"},{"key":"e_1_2_11_17_1","unstructured":"Ornge Air Ambulance.Statistics and Reports.https:\/\/www.ornge.ca\/home. Accessed 27 Mar 2026"},{"key":"e_1_2_11_18_1","unstructured":"Critical Care Services Ontario.Trauma and Burns Programs.https:\/\/criticalcareontario.ca\/solutions\/trauma-burns\/. Accessed 27 Mar 2026"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10389-022-01799-9"},{"key":"e_1_2_11_20_1","doi-asserted-by":"crossref","unstructured":"DaintyKN BrooksSC GrunauB SKline MShore(2023)Impact of the COVID\u201019 on Bystanderism: does a pandemic change the Canadian public's willingness to help during cardiac arrest emergency?(Preprint)https:\/\/doi.org\/10.20944\/preprints202309.1899.v1","DOI":"10.20944\/preprints202309.1899.v1"},{"key":"e_1_2_11_21_1","unstructured":"IPSOS Omnibushttps:\/\/www.ipsos.com\/en\/omnibus-0. Accessed 27 Mar 2026"},{"key":"e_1_2_11_22_1","unstructured":"IPSOS.Credibility intervals for online polling.https:\/\/www.ipsos.com\/sites\/default\/files\/ct\/publication\/documents\/2021-03\/credibility_intervals_for_online_polling_-_2021.pdf. Accessed 27 Mar 2026"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/area.12604"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/14780887.2013.801543"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11135-017-0574-8"},{"key":"e_1_2_11_26_1","first-page":"292","volume-title":"Handbook of research methods in personality psychology","author":"Woike BA","year":"2007"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1037\/13620-004"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.glmedi.2025.100198"},{"issue":"1","key":"e_1_2_11_29_1","first-page":"26","article-title":"Expanding approaches for research: understanding and using trustworthiness in qualitative research","volume":"44","author":"Stahl NA","year":"2020","journal-title":"J Dev Educ"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/medethics-2019-105651"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-026-09592-9"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11019-022-10102-2"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/virtualmentor.2009.11.8.pfor1-0908"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.7591"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2014.06.023"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1570899"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70250","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.70250","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70250","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T18:29:24Z","timestamp":1786213764000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.70250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":35,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/trf.70250"],"URL":"https:\/\/doi.org\/10.1111\/trf.70250","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]},"assertion":[{"value":"2026-04-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}