{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T13:00:06Z","timestamp":1780750806042,"version":"3.54.1"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T00:00:00Z","timestamp":1780704000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T00:00:00Z","timestamp":1780704000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000038","name":"U.S. Food and Drug Administration","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006438","name":"Office of the Assistant Secretary for Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006438","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The US adopted an individual donor assessment (IDA) policy in 2023 to evaluate blood donor risk, potentially resulting in more eligible donors and first\u2010time donors (FTDs). FTDs are associated with higher transfusion\u2010transmissible infectious disease (TTID) risk. Thus, we compared FTD demographics, characteristics, and return behavior during the first 2\u2009years of the IDA compared to the previous 2\u2009years during the 3\u2010month deferral (3MD) policy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>FTD donation data from the transfusion\u2010transmissible infections monitoring system (TTIMS) during the initial 2\u2009years of IDA were compared to the preceding 2\u2009years (3MD). Descriptive statistics were used to assess changes in FTD demographics, donation characteristics, state of residence, and return behavior during the IDA policy compared to the 3MD policy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were slightly over 4 million donations from FTDs during the entire study period, with a 6% increase overall during the IDA period, led mostly by male FTDs (14% increase). Increases were observed in most other demographic\/characteristic groups except for a few (female, aged 16\u201324, or other procedure types). There was a higher absolute number of returning donors and subsequent donations from the FTDs during the IDA period compared to the previous period. The Northeastern US states were found to have the highest increase in FTDs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>There were variable increases in FTDs among most demographic and characteristic groups post\u2010implementation of the IDA policy, notably among men. Although attributability to the new policy is unclear, blood availability may increase with such policies. Continued monitoring will ensure blood safety during donor policy changes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.70269","type":"journal-article","created":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T12:20:02Z","timestamp":1780748402000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First\u2010time blood donor demographics and characteristics during the individual donor assessment versus 3\u2010month deferral policies for high\u2010risk behaviors"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2507-9141","authenticated-orcid":false,"given":"Galen","family":"Conti","sequence":"first","affiliation":[{"name":"American Red Cross Biomedical Services, Medical and Scientific Office  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9106-1858","authenticated-orcid":false,"given":"Emilya","family":"Huseynova","sequence":"additional","affiliation":[{"name":"American Red Cross Biomedical Services, Medical and Scientific Office  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Stramer","sequence":"additional","affiliation":[{"name":"Infectious Disease Consultant  North Potomac Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger Y.","family":"Dodd","sequence":"additional","affiliation":[{"name":"Infectious Disease Consultant  North Potomac Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Reik","sequence":"additional","affiliation":[{"name":"OneBlood  St. Petersburg Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-366X","authenticated-orcid":false,"given":"Brian","family":"Custer","sequence":"additional","affiliation":[{"name":"Vitalant Research Institute  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Engel","sequence":"additional","affiliation":[{"name":"New York Blood Center Enterprises  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benyam","family":"Hailu","sequence":"additional","affiliation":[{"name":"National Heart, Lung, and Blood Institute US National Institutes of Health  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Yang","sequence":"additional","affiliation":[{"name":"US Food and Drug Administration  Silver Spring Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"IV","given":"Edward P.","family":"Notari","sequence":"additional","affiliation":[{"name":"American Red Cross Biomedical Services, Medical and Scientific Office  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,6]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Federal Register.Revised recommendations for reducing the risk of human immunodeficiency virus transmission by blood and blood products; Guidance for industry. Available from:https:\/\/www.federalregister.gov\/documents\/2015\/12\/23\/2015-32250\/revised-recommendations-for-reducing-the-risk-of-human-immunodeficiency-virus-transmission-by-blood. Accessed December 29 2025."},{"key":"e_1_2_9_3_1","unstructured":"US Food and Drug Administration.Revised recommendations for reducing the risk of human immunodeficiency virus transmission by blood and blood products. Available from:https:\/\/collections.nlm.nih.gov\/catalog\/nlm:nlmuid-9918227270706676-pdf. Accessed December 29 2025."},{"key":"e_1_2_9_4_1","unstructured":"US Food and Drug Administration.Recommendations for Evaluating Donor Eligibility Using Individual Risk\u2010Based Questions to Reduce the Risk of Human Immunodeficiency Virus Transmission by Blood and Blood Products. Available from:https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/recommendations-evaluating-donor-eligibility-using-individual-risk-based-questions-reduce-risk-human. Accessed December 29 2025."},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18424"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16005"},{"key":"e_1_2_9_7_1","volume-title":"LGBTQ+ identification in U.S. rises to 9.3%","author":"Gallup","year":"2025"},{"key":"e_1_2_9_8_1","unstructured":"American Red Cross.LGBTQ+ History Month: LGBTQ+ community makes lifesaving contributions through Red Cross after historic change in blood donation eligibility.2024Available from:https:\/\/www.redcross.org\/about\u2010us\/news\u2010and\u2010events\/news\/2024\/LGBTQ\u2010history\u2010month\u2010LGBTQ\u2010community\u2010makes\u2010lifesaving\u2010contributions\u2010through\u2010red\u2010cross\u2010after\u2010historic\u2010change\u2010in\u2010blood\u2010donation\u2010eligibility.html."},{"key":"e_1_2_9_9_1","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.tmrv.2022.06.007","article-title":"Actions and attitudes of men who have sex with men under past, current, and hypothetical future blood donation deferral policies","volume":"36","author":"Johns CN","year":"2022","journal-title":"Transfus Med Rev"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1111\/trf.18299","article-title":"Reinstatement and infectious disease rates among blood donors previously deferred under men who have sex with men time\u2010based deferral","volume":"65","author":"Groves J","year":"2025","journal-title":"Transfusion"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2020.306071"},{"key":"e_1_2_9_12_1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/trf.18168","article-title":"Assessing HIV trends among blood donors in five Brazilian blood centers: the impact of individual donor assessment","volume":"65","author":"Buccheri R","year":"2025","journal-title":"Transfusion"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1111\/vox.12933","article-title":"Gender\u2010neutral donor deferral policies: experience in Argentina implementing individual risk\u2010assessment policies","volume":"115","author":"Blanco S","year":"2020","journal-title":"Vox Sang"},{"key":"e_1_2_9_14_1","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1111\/trf.17878","article-title":"Implementation of sexual risk behavior donor screening in Canada","volume":"64","author":"Goldman M","year":"2024","journal-title":"Transfusion"},{"key":"e_1_2_9_15_1","unstructured":"U.S. Department of Health and Human Services Office of Infectious Disease and HIV\/AIDS Policy.National Blood Collection & Utilization Survey.2024Available from:https:\/\/www.hhs.gov\/oidp\/topics\/blood-tissue-safety\/surveys\/national-blood-collection-and-utilization-survey\/index.html. Accessed January 23 2026."},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17851"},{"key":"e_1_2_9_17_1","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1111\/j.1423-0410.2005.00593.x","article-title":"First year donation patterns predict long\u2010term commitment for first\u2010time donors","volume":"88","author":"Schreiber GB","year":"2005","journal-title":"Vox Sang"},{"key":"e_1_2_9_18_1","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/trf.18098","article-title":"How do we engage with the lesbian, gay, bisexual, and transgender community in blood donation and research? Reflections from the assessing donor variability and new concepts in eligibility study","volume":"65","author":"Crowder LA","year":"2025","journal-title":"Transfusion"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70269","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.70269","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70269","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T12:20:06Z","timestamp":1780748406000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.70269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,6]]},"references-count":17,"alternative-id":["10.1111\/trf.70269"],"URL":"https:\/\/doi.org\/10.1111\/trf.70269","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,6]]},"assertion":[{"value":"2026-03-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"trf.70269"}}