{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:30:25Z","timestamp":1790375425074,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T00:00:00Z","timestamp":1782604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T00:00:00Z","timestamp":1782604800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Standardized guidance regarding the processes for collecting directed blood donations (DBD) is lacking, leading to variable practices. This study assessed laboratory, clinical, and charging practices for DBD collection in the United States and Canada.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design and Methods<\/jats:title>\n                    <jats:p>An electronic survey was distributed to United States and Canadian blood collection centers and hospitals to evaluate institutional demographics, policies, indications, medical oversight, and financial responsibility for DBD collection.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Survey respondents included 193 hospitals and 10 blood collection centers with a response rate of 34% (203\/594). Red blood cells were the most commonly collected DBD product. Fifty percent (5\/10) of blood center respondents did not include the rationale for the DBD request on requisitions. Non\u2010medical requests were accommodated by 70% (7\/10) of blood centers and 42% (81\/193) of hospitals. Transfusion Medicine review was not required by 48% (98\/203). Safety practices also varied: only 60% (53\/88) verify donor\u2010recipient ABO suitability prior to collection, and 57% (50\/88) had no additional exclusion criteria for high\u2010risk related donors. Forty\u2010four percent of respondents reported additional charges, but many hospitals reported uncertainty about billing. Most hospitals (59%) reported wasting DBD units, with higher discard rates among those that do not return units to general inventory.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Heterogeneous DBD practices reflect the absence of standard policies. Lack of oversight and safety checks may expose patients to unnecessary risks. The authors outline key considerations for DBD requests to standardize safeguards, including defined exclusion criteria for high\u2010risk donor\u2010recipient pairs and education on DBD risks.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.70279","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T06:25:22Z","timestamp":1782714322000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<scp>AABB<\/scp>\n                    survey on directed blood donation practices"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1646-9201","authenticated-orcid":false,"given":"Nabiha H.","family":"Saifee","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Seattle Children's and University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7199-5821","authenticated-orcid":false,"given":"Emily","family":"Coberly","sequence":"additional","affiliation":[{"name":"American Red Cross  Maryland Heights Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9480-2762","authenticated-orcid":false,"given":"Brian D.","family":"Adkins","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Texas Southwestern Medical Center  Dallas Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7836-0132","authenticated-orcid":false,"given":"Louise","family":"Helander","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Colorado  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0450-1818","authenticated-orcid":false,"given":"Nancy","family":"Robitaille","sequence":"additional","affiliation":[{"name":"Transfusion Medicine H\u00e9ma\u2010Qu\u00e9bec  Montr\u00e9al Qu\u00e9bec Canada"},{"name":"Division of Hematology and Oncology, Department of Pediatrics CHU Sainte\u2010Justine  Montr\u00e9al Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9101-9326","authenticated-orcid":false,"given":"Laura K.","family":"Dilly","sequence":"additional","affiliation":[{"name":"Department of Pathology University of California San Diego  San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3633-0728","authenticated-orcid":false,"given":"Lani","family":"Lieberman","sequence":"additional","affiliation":[{"name":"Laboratory Medicine Program (Transfusion Medicine) University Health Network  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,28]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"NesterT AlcornK BollagRJ FredrichN GoelR HermelinD et al.Helping patients understand potential limitations of directed donation requests. Blood Bulletin. 2025 [cited 2026 Feb 7]. Available from:https:\/\/americasblood.org\/wp\u2010content\/uploads\/2025\/10\/2510_BloodBulletin_directed_donations.pdf"},{"key":"e_1_2_9_3_1","unstructured":"U.S. Food and Drug Administration.Important information about directed blood donations that are not medically indicated. 2023 [cited 2026 Feb 7]. 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Available from:https:\/\/americasblood.org\/abc\u2010news\/states\u2010are\u2010moving\u2010quickly\u2010on\u2010bills\u2010related\u2010to\u2010directed\u2010and\u2010autologous\u2010donations\u2010and\u2010vaccination\u2010status\u2010labeling\/#:~:text=February%2018 %202026\u2010 States%20Are%20Moving%20Quickly%20on%20Bills%20Related%20to%20Directed Donations%20and%20Vaccination%20Status%20Labeling&text=State%20legislatures%20continue%20to%20see 1171%20and%20TN%20SB%200828"},{"key":"e_1_2_9_15_1","unstructured":"America's Blood Centers.Legislation we're watching. [cited 2026 April 17]. Available from:https:\/\/americasblood.org\/advocacy\/legislation-were-watching\/"},{"key":"e_1_2_9_16_1","unstructured":"Association for the Advancement of Blood and Biotherapies (AABB).Position statement: policy proposals containing requirements for directed or autologous blood donations. 2024 [cited 2026 May 2]. Available from:https:\/\/www.aabb.org\/docs\/default\u2010source\/default\u2010document\u2010library\/positions\/aabb\u2010position\u2010statement\u2010policy\u2010proposals\u2010containing\u2010requirements\u2010for\u2010directed\u2010or\u2010autologous\u2010blood\u2010donations.pdf"},{"key":"e_1_2_9_17_1","volume-title":"Blood transfusions: information for patients","author":"Medical Board of California","year":"2022"},{"key":"e_1_2_9_18_1","volume-title":"Directed blood product transfusion","author":"Idaho House Bill 528","year":"2026"},{"issue":"2","key":"e_1_2_9_19_1","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014a metadata\u2010driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris PA","year":"2009","journal-title":"J Biomed Inform"},{"key":"e_1_2_9_20_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbi.2019.103208","article-title":"The REDCap consortium: building an international community of software platform partners","volume":"95","author":"Harris PA","year":"2019","journal-title":"J Biomed Inform"},{"key":"e_1_2_9_21_1","unstructured":"American Red Cross.Donation dedication. 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