{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:43:57Z","timestamp":1792158237960,"version":"4.4.0"},"reference-count":11,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Cryogenic storage of cord blood units (CBUs) is critical to ensure long\u2010term viability and safety. Loss of vacuum in liquid nitrogen (LN\n                      <jats:sub>2<\/jats:sub>\n                      ) tanks is an exceptionally rare but high\u2010risk event that may lead to accelerated LN\n                      <jats:sub>2<\/jats:sub>\n                      evaporation and potential warming of stored units.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Report<\/jats:title>\n                    <jats:p>\n                      We describe an emergency rescue transfer following suspected vacuum loss in a BioArchive cryogenic tank at a public cord blood bank. The tank contained 2880 CBUs, including 14 directed units. Progressive LN\n                      <jats:sub>2<\/jats:sub>\n                      consumption suggested structural failure, and in situ repair was not feasible. A rapid transfer procedure using a backup BioArchive\u2010compatible tank was performed with the assistance of the manufacturer. The maneuver involved crane\u2010assisted repositioning of the tank under the robotic system and was completed in 40\u2009s. Continuous temperature monitoring confirmed stable vapor\u2010phase conditions throughout the procedure. Six CBUs stored in upper tank positions (worst\u2010case exposure) were evaluated post\u2010thaw. Cell recovery, viability, and clonogenic capacity were preserved and met release criteria for transplantation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Emergency transfer of CBUs during cryogenic tank malfunction is feasible and can be performed safely without compromising product quality when executed under controlled conditions. This report provides practical guidance for managing rare but critical storage failures in cord blood banking using BioArchive system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.70330","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T14:40:30Z","timestamp":1783953630000},"page":"2037-2041","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Emergency whole\u2010tank transfer of cord blood units after cryogenic failure: A safe rescue strategy"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4016-0020","authenticated-orcid":false,"given":"Jesus","family":"Fernandez\u2010Sojo","sequence":"first","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Azqueta","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nerea","family":"Castillo\u2010Flores","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f2nica","family":"Linares","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Valdivia","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Medina\u2010Boronat","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital Universitari Vall d'Hebron  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Arteaga","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Rubio","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia","family":"Poyatos","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Guterres","sequence":"additional","affiliation":[{"name":"Concessus  Sintra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Garcia\u2010Buendia","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1105-8633","authenticated-orcid":false,"given":"Sergi","family":"Querol","sequence":"additional","affiliation":[{"name":"REDMO (Spanish Bone Marrow Donor Registry) Fundaci\u00f3 Josep Carreras  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan R.","family":"Grifols","sequence":"additional","affiliation":[{"name":"Banc de Sang i Teixits  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198910263211707"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-019-0546-9"},{"key":"e_1_2_8_4_1","unstructured":"World Marrow Donor Association (WMDA).Global trends report. 2024. Available from:https:\/\/share.wmda.info\/spaces\/SupportingGlobalDevelopment\/pages\/570818667\/Global+Trends+Report+2024(accessed April 2026)."},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/stcltm\/szad071"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/stcltm\/szad072"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cryobiol.2017.07.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-019-01597-5"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-019-01402-3"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1515\/labmed-2022-0167"},{"key":"e_1_2_8_11_1","volume-title":"International standards for cord blood collection, banking, and release for administration","author":"FACT\u2013NetCord","year":"2024"},{"key":"e_1_2_8_12_1","unstructured":"European Parliament and Council.Regulation (EU) 2024\/1938 on standards of quality and safety for substances of human origin intended for human application. Off J Eur Union. 2024."}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.70330","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70330","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T12:44:30Z","timestamp":1792154670000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.70330"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,13]]},"references-count":11,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/trf.70330"],"URL":"https:\/\/doi.org\/10.1111\/trf.70330","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,13]]},"assertion":[{"value":"2026-04-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}