{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:00:13Z","timestamp":1790319613192,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cell processing facility accreditation requires Medical Directors and Laboratory Directors, but formal training pathways are not systematically delineated. This study provides information on cell processing facility Medical Directors and Laboratory Directors' role\u2010specific education (RSE) worldwide.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design and Methods<\/jats:title>\n                    <jats:p>Data collected on cell processing facilities included country, staff, regulatory and accreditation status, institutional affiliation, cellular therapy product types, and volume. Questions regarding Medical Directors included country, clinical specialty and subspecialty, year completed, and formal RSE. Laboratory Director questions included country and training focus, year completed, and formal RSE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Surveys completed (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009123) included Medical Directors (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200970) and Laboratory Directors (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200971) across 30 countries over 6 continents. Medical Directors reported 101 clinical specialties, and 72 clinical subspecialties, of which 34 (33.3%) and 39 (54.2%) included RSE, respectively. Laboratory Directors (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200971) held MD (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200920), PhD (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200934), MD\/PhD (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20097), or other (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911) academic degrees. Laboratory Directors with MDs completed 42 clinical specialties and 27 clinical subspecialties, 15 (35.8%) and 13 (48.1%) of which included RSE, respectively. Six of 52 (11.5%) Laboratory Directors with graduate or other academic degrees (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200952) included RSE. Role\u2010specific educational experiences varied highly across all training programs. Notably, most responses for any given role and educational activity indicated no experience at all.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Standardized role\u2010specific educational programs for cell processing facility Medical Directors and Laboratory Directors are lacking and, when present, are highly variable. Coordinated development of educational content and reciprocally acknowledged curricula and certificates could help standardize training for future cell processing facility leaders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/trf.70369","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:26:20Z","timestamp":1790317580000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Global evaluation of cellular therapy processing facility medical director and laboratory director training: The BEST collaborative study"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9881-703X","authenticated-orcid":false,"given":"Suzanne R.","family":"Thibodeaux","sequence":"first","affiliation":[{"name":"Department of Pathology &amp; Immunology WashU Medicine  St. Louis Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9715-7743","authenticated-orcid":false,"given":"Anh","family":"Dinh","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine and Center for Cellular Engineering National Institutes of Health Clinical Center  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u2010Anna","family":"Reems","sequence":"additional","affiliation":[{"name":"Merakris Therapeutics  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1530-7980","authenticated-orcid":false,"given":"Richard","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"Institute for Transfusion Medicine and Gene Therapy, Medical Center University of Freiburg  Freiburg im Breisgau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Foundation for the Accreditation of Cellular Therapy  Omaha Nebraska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5090-0328","authenticated-orcid":false,"given":"Linda S.","family":"Barnes","sequence":"additional","affiliation":[{"name":"Linda S Barnes Consulting, Seattle, WA, USA; Strathmore University  Nairobi Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phyllis","family":"Warkentin","sequence":"additional","affiliation":[{"name":"Foundation for the Accreditation of Cellular Therapy  Omaha Nebraska USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8734-0996","authenticated-orcid":false,"given":"David H.","family":"McKenna","sequence":"additional","affiliation":[{"name":"Molecular &amp; Cellular Therapeutics, University of Minnesota  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the Biomedical Excellence for Safer Transfusion (BEST) Collaborative","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Association for the Advancement of Blood and Biotherapies.Standards for cellular therapy services. 1.1.4.1 laboratory medical director. Eleventh Edition July 1 2023."},{"key":"e_1_2_9_3_1","unstructured":"Foundation for the Accreditation of Cellular Therapy.Processing facility medical director (standard D3.2). International standards for hematopoietic cellular therapy product collection processing and administration. Eighth Edition Version 8.1 December 14 2021."},{"key":"e_1_2_9_4_1","unstructured":"Association for the Advancement of Blood and Biotherapies.Standards for cellular therapy services. 1.1.4.2 laboratory director. Eleventh Edition July 1 2023."},{"key":"e_1_2_9_5_1","unstructured":"Foundation for the Accreditation of Cellular Therapy.Processing facility director (standard D3.1). International standards for hematopoietic cellular therapy product collection processing and administration. Eighth Edition Version 8.1 December 14 2021."},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16601"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmrv.2016.11.003"},{"key":"e_1_2_9_8_1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1002\/jca.21845","article-title":"Current state of therapeutic apheresis and cellular therapy education for transfusion medicine fellows in the United States","volume":"36","author":"Pham HP","year":"2020","journal-title":"J Clin Apher"},{"key":"e_1_2_9_9_1","unstructured":"Accreditation Council for Graduate Medical Education.Blood banking and transfusion medicine milestones.2021. Available from:https:\/\/www.acgme.org\/globalassets\/pdfs\/milestones\/bloodbankingtransfusionmedicinemilestones.pdf. Accessed 13 Nov 2025."},{"key":"e_1_2_9_10_1","unstructured":"American Board of Pathology.Blood banking\/transfusion medicine exam blueprint.2024. Available from:https:\/\/abpath.org\/wp-content\/uploads\/2024\/02\/BBTM_SS_2024.pdf. Accessed 13 Nov 2025."},{"key":"e_1_2_9_11_1","unstructured":"The American Board of Pathology.Blood banking and transfusion medicine content specifications. Available from:https:\/\/abpath.org\/wp\u2010content\/uploads\/2024\/11\/Content\u2010Specification\u2010BBTM_SSmaster_Final_10292024_nmbred.pdf. Accessed 13 Nov 2025."},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.70021"},{"key":"e_1_2_9_13_1","unstructured":"The Association for the Advancement of Blood and Biotherapies.Certified advanced biotherapies professional (CABP) credential. Available from:https:\/\/www.aabb.org\/education\u2010career\/career\/certified\u2010advanced\u2010biotherapies\u2010professional\u2010credential. Accessed 15 Feb 2026."}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70369","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.70369","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70369","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:26:22Z","timestamp":1790317582000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.70369"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,24]]},"references-count":12,"alternative-id":["10.1111\/trf.70369"],"URL":"https:\/\/doi.org\/10.1111\/trf.70369","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,24]]},"assertion":[{"value":"2026-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"trf.70369"}}