{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T12:18:05Z","timestamp":1788178685362,"version":"build-2803163510"},"reference-count":69,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Transfusion"],"DOI":"10.1111\/trf.70381","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:48:33Z","timestamp":1788176913000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Current advances in 2025: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (\n                    <scp>AABB<\/scp>\n                    ) Clinical Transfusion Medicine Committee"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1646-9201","authenticated-orcid":false,"given":"Nabiha H.","family":"Saifee","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine and Pathology Seattle Children's and University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3801-4198","authenticated-orcid":false,"given":"Jennifer","family":"Andrews","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology, and Immunology Vanderbilt University  Nashville Tennessee USA"},{"name":"Department of Pediatrics Vanderbilt University  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4961-245X","authenticated-orcid":false,"given":"Mary","family":"Berg","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Colorado School of Medicine and UCHealth  Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4333-6965","authenticated-orcid":false,"given":"Stella T.","family":"Chou","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5452-4529","authenticated-orcid":false,"given":"Mischa","family":"Covington","sequence":"additional","affiliation":[{"name":"Department of Pathology Brigham and Women's Hospital and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1910-2800","authenticated-orcid":false,"given":"Elizabeth P.","family":"Crowe","sequence":"additional","affiliation":[{"name":"Department of Pathology Johns Hopkins University  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9653-9905","authenticated-orcid":false,"given":"Ruchika","family":"Goel","sequence":"additional","affiliation":[{"name":"Department of Pathology Johns Hopkins University  Baltimore Maryland USA"},{"name":"Carter BloodCare  Bedford Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0826-0088","authenticated-orcid":false,"given":"Juliana A.","family":"Guarente","sequence":"additional","affiliation":[{"name":"Department of Pathology and Genomic Medicine Thomas Jefferson University Hospital  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3554-5521","authenticated-orcid":false,"given":"Tina","family":"Ipe","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Arkansas  Little Rock Arkansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5719-9685","authenticated-orcid":false,"given":"Jeremy W.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology, and Immunology Vanderbilt University  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8847-2763","authenticated-orcid":false,"given":"Jessica","family":"Jacobson","sequence":"additional","affiliation":[{"name":"Department of Pathology NYU Grossman School of Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1281-0644","authenticated-orcid":false,"given":"Cyril","family":"Jacquot","sequence":"additional","affiliation":[{"name":"Children's National Hospital  Washington DC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Virginia  Charlottesville Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-5247-658X","authenticated-orcid":false,"given":"Thane A.","family":"Kubik","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Calgary  Calgary Alberta Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3474-576X","authenticated-orcid":false,"given":"Theodros","family":"Mamo","sequence":"additional","affiliation":[{"name":"OhioHealth Arthur G.H. Bing, MD, Cancer Center Blood and Marrow Transplant and Cellular Therapy Program  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2375-7503","authenticated-orcid":false,"given":"Michael F.","family":"Murphy","sequence":"additional","affiliation":[{"name":"NHS Blood and Transplant, Oxford University Hospitals NHS Foundation Trust, and the University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerry","family":"O'Brien","sequence":"additional","affiliation":[{"name":"Department of Pathology Beth Israel Deaconess Medical Center and Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5183-6471","authenticated-orcid":false,"given":"Monica B.","family":"Pagano","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil K.","family":"Panigrahi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Perioperative and Pain Medicine, and Pathology Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2431-5106","authenticated-orcid":false,"given":"Jacqueline N.","family":"Poston","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine University of Vermont  Burlington Vermont USA"},{"name":"Department of Medicine University of Vermont  Burlington Vermont USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5641-1007","authenticated-orcid":false,"given":"Scott E.","family":"Potter","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine Geisel School of Medicine at Dartmouth  Lebanon New Hampshire USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7414-4950","authenticated-orcid":false,"given":"Simon J.","family":"Stanworth","sequence":"additional","affiliation":[{"name":"NHS Blood and Transplant, Oxford University Hospitals NHS Foundation Trust, and the University of Oxford  Oxford UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2866-1674","authenticated-orcid":false,"given":"Moritz","family":"Stolla","sequence":"additional","affiliation":[{"name":"Bloodworks Northwest Research Institute  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1814-9319","authenticated-orcid":false,"given":"Alyssa","family":"Ziman","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine David Geffen School of Medicine at UCLA  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6074-7147","authenticated-orcid":false,"given":"Ryan A.","family":"Metcalf","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"e_1_2_17_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2025.103426"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000006640"},{"key":"e_1_2_17_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.23355"},{"key":"e_1_2_17_5_1","unstructured":"Association for the Advancement of Blood and Biotherapies (AABB).Medication Deferral List (DHQ\/aDHB v4.0) Published July 25. Accessed April 5 2026.https:\/\/www.aabb.org\/docs\/default\u2010source\/default\u2010document\u2010library\/resources\/dhq\u2010v4\u20100\/pdfs\/dhq\u2010adhq\u2010v4\u20100\u2010mdl.pdf"},{"key":"e_1_2_17_6_1","unstructured":"Association for the Advancement of Blood and Biotherapies (AABB).Medication Deferral List v4.0\u2014Updated July 2025 Yeztugo (Lenacapavir)\u2014Toolkit for Implementation Published July 9 2025. Accessed April 5 2026.https:\/\/www.aabb.org\/docs\/default\u2010source\/default\u2010document\u2010library\/regulatory\/medication\u2010deferral\u2010list\u2010v4\u20100\u2010toolkit\u2010for\u2010implementation.pdf?sfvrsn=1ba5dcb5_3"},{"key":"e_1_2_17_7_1","unstructured":"Yeztugo\u00ae: Full Prescribing Information. Athttps:\/\/www.gilead.com\/-\/media\/files\/pdfs\/medicines\/hiv\/yeztugo\/yeztugo_pi.pdf. Accessed April 5 2026."},{"key":"e_1_2_17_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18195"},{"key":"e_1_2_17_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18424"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18145"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid3109.241700"},{"key":"e_1_2_17_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002042.pub5"},{"key":"e_1_2_17_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.20841"},{"key":"e_1_2_17_14_1","doi-asserted-by":"publisher","DOI":"10.7326\/ANNALS-25-00706"},{"key":"e_1_2_17_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001309"},{"key":"e_1_2_17_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2025.05.019"},{"key":"e_1_2_17_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.7529"},{"key":"e_1_2_17_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.3501"},{"key":"e_1_2_17_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2025.09.009"},{"key":"e_1_2_17_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezae352"},{"key":"e_1_2_17_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2024.06.039"},{"key":"e_1_2_17_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.3644"},{"key":"e_1_2_17_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.8991"},{"key":"e_1_2_17_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.32702"},{"key":"e_1_2_17_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2025.03.038"},{"key":"e_1_2_17_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2025.06.002"},{"key":"e_1_2_17_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(24)00376-4"},{"key":"e_1_2_17_28_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2025016554"},{"key":"e_1_2_17_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)00635-X"},{"key":"e_1_2_17_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(24)00319-3"},{"key":"e_1_2_17_31_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202409-1727OC"},{"key":"e_1_2_17_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2025.114797"},{"key":"e_1_2_17_33_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2020248"},{"key":"e_1_2_17_34_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.10690"},{"key":"e_1_2_17_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1807320"},{"key":"e_1_2_17_36_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.54330"},{"key":"e_1_2_17_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.14194"},{"key":"e_1_2_17_38_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.14389"},{"key":"e_1_2_17_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18367"},{"key":"e_1_2_17_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2025.04.008"},{"key":"e_1_2_17_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18128"},{"key":"e_1_2_17_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18125"},{"key":"e_1_2_17_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18072"},{"key":"e_1_2_17_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18253"},{"key":"e_1_2_17_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2025.104208"},{"key":"e_1_2_17_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xkme.2025.101105"},{"key":"e_1_2_17_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.70035"},{"key":"e_1_2_17_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.70017"},{"key":"e_1_2_17_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2025.103168"},{"key":"e_1_2_17_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1700907"},{"key":"e_1_2_17_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18262"},{"key":"e_1_2_17_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.70038"},{"key":"e_1_2_17_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/jca.70049"},{"key":"e_1_2_17_54_1","unstructured":"ClinicalTrials.gov.Search results for autoimmune diseases AND cell therapy; status: recruiting or active. National Library of Medicine. Accessed January 28 2026.https:\/\/clinicaltrials.gov\/search?cond=Autoimmune%20Diseases&intr=cell%20therapy&aggFilters=status%3Arec%20act&page=31"},{"key":"e_1_2_17_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-04185-6"},{"key":"e_1_2_17_56_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2025031313"},{"key":"e_1_2_17_57_1","unstructured":"US Food and Drug Administration.FDA Approves First Gene Therapy Treatment for Wiskott\u2010Aldrich Syndrome. FDA News Release. Published December 9 2025. Accessed January 30 2026.https:\/\/www.fda.gov\/news\u2010events\/press\u2010announcements\/fda\u2010approves\u2010first\u2010gene\u2010therapy\u2010treatment\u2010wiskott\u2010aldrich\u2010syndrome"},{"key":"e_1_2_17_58_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsb2512695"},{"key":"e_1_2_17_59_1","unstructured":"US Food and Drug Administration.FDA eliminates Risk Evaluation and Mitigation Strategies (REMS) for autologous chimeric antigen receptor (CAR) T\u2010cell immunotherapies. FDA News Release. Published June 26 2025. Accessed January 29 2026.https:\/\/www.fda.gov\/news\u2010events\/press\u2010announcements\/fda\u2010eliminates\u2010risk\u2010evaluation\u2010and\u2010mitigation\u2010strategies\u2010rems\u2010autologous\u2010chimeric\u2010antigen\u2010receptor"},{"key":"e_1_2_17_60_1","unstructured":"The Human Medicines (Amendment) (Modular Manufacture and Point of Care) Regulations 2025 SI 2025\/87 (UK). Made January 23 2025; coming into force July 23 2025. Accessed January 28 2026.https:\/\/www.legislation.gov.uk\/uksi\/2025\/87\/contents\/made"},{"key":"e_1_2_17_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2025.101358"},{"key":"e_1_2_17_62_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2025.2513003"},{"key":"e_1_2_17_63_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2025.2997"},{"key":"e_1_2_17_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2025.118452"},{"key":"e_1_2_17_65_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.43421"},{"key":"e_1_2_17_66_1","doi-asserted-by":"publisher","DOI":"10.1097\/MS9.0000000000004195"},{"key":"e_1_2_17_67_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474086.2025.2610282"},{"key":"e_1_2_17_68_1","doi-asserted-by":"publisher","DOI":"10.7326\/ANNALS-25-00815"},{"key":"e_1_2_17_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.18312"},{"key":"e_1_2_17_70_1","unstructured":"Association for the Advancement of Blood and Biotherapies (AABB).Position statement: policy proposals containing requirements for directed or autologous blood donations.2024. Accessed April 4 2026.https:\/\/www.aabb.org\/docs\/default\u2010source\/default\u2010document\u2010library\/positions\/aabb\u2010position\u2010statement\u2010policy\u2010proposals\u2010containing\u2010requirements\u2010for\u2010directed\u2010or\u2010autologous\u2010blood\u2010donations.pdf"}],"container-title":["Transfusion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70381","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/trf.70381","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/trf.70381","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:48:35Z","timestamp":1788176915000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/trf.70381"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":69,"alternative-id":["10.1111\/trf.70381"],"URL":"https:\/\/doi.org\/10.1111\/trf.70381","archive":["Portico"],"relation":{},"ISSN":["0041-1132","1537-2995"],"issn-type":[{"value":"0041-1132","type":"print"},{"value":"1537-2995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"assertion":[{"value":"2026-05-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"trf.70381"}}