{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:50:36Z","timestamp":1761630636299},"reference-count":67,"publisher":"Frontiers Media SA","issue":"2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":992,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transpl Int"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1111\/tri.12021","type":"journal-article","created":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T00:28:25Z","timestamp":1355444905000},"page":"206-218","source":"Crossref","is-referenced-by-count":13,"title":["Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients"],"prefix":"10.3389","volume":"26","author":[{"given":"Haley","family":"Ramsey","sequence":"first","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Pilat","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Hock","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Klaus","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas","family":"Unger","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Schwarz","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike","family":"Baranyi","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Gattringer","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Schwaiger","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fritz","family":"Wrba","sequence":"additional","affiliation":[{"name":"Institute of Clinical Pathology; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Wekerle","sequence":"additional","affiliation":[{"name":"Division of Transplantation; Department of Surgery; Medical University of Vienna; Vienna; Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2012,12,13]]},"reference":[{"key":"10.1111\/tri.12021-BIB0001|tri12021-cit-0001","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/nrneph.2010.110","article-title":"Transplantation tolerance through mixed chimerism","volume":"6","author":"Pilat","year":"2010","journal-title":"Nat Rev Nephrol"},{"key":"10.1111\/tri.12021-BIB0002|tri12021-cit-0002","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1056\/NEJMoa071074","article-title":"HLA-mismatched renal transplantation without maintenance immunosuppression","volume":"358","author":"Kawai","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1111\/tri.12021-BIB0003|tri12021-cit-0003","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1056\/NEJMoa074191","article-title":"Tolerance and chimerism after renal and hematopoietic-cell transplantation","volume":"358","author":"Scandling","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1111\/tri.12021-BIB0004|tri12021-cit-0004","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/j.1600-6143.2006.01260.x","article-title":"Transplant tolerance in non-human primates: progress, current challenges and unmet needs","volume":"6","author":"Kean","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0005|tri12021-cit-0005","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1038\/74731","article-title":"Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment","volume":"6","author":"Wekerle","year":"2000","journal-title":"Nat Med"},{"key":"10.1111\/tri.12021-BIB0006|tri12021-cit-0006","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4049\/jimmunol.165.1.1","article-title":"Administration of anti-CD40 ligand and donor bone marrow leads to hematopoietic chimerism and donor-specific tolerance without cytoreductive conditioning","volume":"165","author":"Durham","year":"2000","journal-title":"J Immunol"},{"key":"10.1111\/tri.12021-BIB0007|tri12021-cit-0007","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1182\/blood-2002-10-3014","article-title":"The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade","volume":"101","author":"Blaha","year":"2003","journal-title":"Blood"},{"key":"10.1111\/tri.12021-BIB0008|tri12021-cit-0008","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1182\/blood.V98.2.467","article-title":"Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions","volume":"98","author":"Taylor","year":"2001","journal-title":"Blood"},{"key":"10.1111\/tri.12021-BIB0009|tri12021-cit-0009","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1046\/j.1600-6135.2003.00272.x","article-title":"Earlier low-dose TBI or DST overcomes CD8+ T-cell-mediated alloresistance to allogeneic marrow in recipients of anti-CD40L","volume":"4","author":"Takeuchi","year":"2004","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0010|tri12021-cit-0010","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/TP.0b013e31819535c2","article-title":"Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials","volume":"87","author":"Sykes","year":"2009","journal-title":"Transplantation"},{"key":"10.1111\/tri.12021-BIB0011|tri12021-cit-0011","doi-asserted-by":"crossref","first-page":"4248","DOI":"10.2741\/2384","article-title":"Induction of allograft tolerance in nonhuman primates and humans","volume":"12","author":"Ochiai","year":"2007","journal-title":"Front Biosci"},{"key":"10.1111\/tri.12021-BIB0012|tri12021-cit-0012","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1084\/jem.187.12.2037","article-title":"Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance","volume":"187","author":"Wekerle","year":"1998","journal-title":"J Exp Med"},{"key":"10.1111\/tri.12021-BIB0013|tri12021-cit-0013","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.4049\/jimmunol.167.2.1103","article-title":"Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression","volume":"167","author":"Adams","year":"2001","journal-title":"J Immunol"},{"key":"10.1111\/tri.12021-BIB0014|tri12021-cit-0014","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/S0952-7915(02)00378-3","article-title":"Mechanisms of transplant tolerance induction using costimulatory blockade","volume":"14","author":"Wekerle","year":"2002","journal-title":"Curr Opin Immunol"},{"key":"10.1111\/tri.12021-BIB0015|tri12021-cit-0015","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1111\/j.1600-6143.2004.00523.x","article-title":"CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates","volume":"4","author":"Kawai","year":"2004","journal-title":"Am J Transpl"},{"key":"10.1111\/tri.12021-BIB0016|tri12021-cit-0016","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1111\/j.1600-6143.2010.03272.x","article-title":"An MHC-defined primate model reveals significant rejection of bone marrow after mixed chimerism induction despite full MHC matching","volume":"10","author":"Larsen","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0017|tri12021-cit-0017","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1084\/jem.187.8.1335","article-title":"Tolerization of anti-Gala1-3Gal natural antibody-forming B cells by induction of mixed chimerism","volume":"187","author":"Yang","year":"1998","journal-title":"The J Exp Med"},{"key":"10.1111\/tri.12021-BIB0018|tri12021-cit-0018","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1111\/j.1600-6143.2009.02738.x","article-title":"B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans","volume":"9","author":"Porcheray","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0019|tri12021-cit-0019","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1111\/j.1600-6143.2010.03087.x","article-title":"Recent progress and new perspectives in studying T cell responses to allografts","volume":"10","author":"Valujskikh","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0020|tri12021-cit-0020","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1097\/MOT.0b013e328332bd4a","article-title":"Memory T-cell-specific therapeutics in organ transplantation","volume":"14","author":"Page","year":"2009","journal-title":"Curr Opin Organ Transplant"},{"key":"10.1111\/tri.12021-BIB0021|tri12021-cit-0021","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1146\/annurev.immunol.22.012703.104702","article-title":"Central memory and effector memory T cell subsets: function, generation, and maintenance","volume":"22","author":"Sallusto","year":"2004","journal-title":"Annu Rev Immunol"},{"key":"10.1111\/tri.12021-BIB0022|tri12021-cit-0022","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1172\/JCI200317477","article-title":"Heterologous immunity provides a potent barrier to transplantation tolerance","volume":"111","author":"Adams","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1111\/tri.12021-BIB0023|tri12021-cit-0023","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nm965","article-title":"Homeostatic proliferation is a barrier to transplantation tolerance","volume":"10","author":"Wu","year":"2004","journal-title":"Nat Med"},{"key":"10.1111\/tri.12021-BIB0024|tri12021-cit-0024","doi-asserted-by":"crossref","first-page":"637","DOI":"10.4049\/jimmunol.165.2.637","article-title":"The abrogation of allosensitization following the induction of mixed allogeneic chimerism","volume":"165","author":"Colson","year":"2000","journal-title":"J Immunol"},{"key":"10.1111\/tri.12021-BIB0025|tri12021-cit-0025","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1097\/01.tp.0000235589.66683.0e","article-title":"Critical roles of memory T cells and antidonor immunoglobulin in rejection of allogeneic bone marrow cells in sensitized recipient mice","volume":"82","author":"Nagata","year":"2006","journal-title":"Transplantation"},{"key":"10.1111\/tri.12021-BIB0026|tri12021-cit-0026","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1034\/j.1600-6143.2003.00123.x","article-title":"T-cell allorecognition and transplant rejection: a summary and update","volume":"3","author":"Heeger","year":"2003","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0027|tri12021-cit-0027","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1034\/j.1600-6143.2002.20603.x","article-title":"Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice","volume":"2","author":"Valujskikh","year":"2002","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0028|tri12021-cit-0028","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.4049\/jimmunol.180.5.3190","article-title":"Expansion of effector memory TCR Vbeta4+ CD8+ T cells is associated with latent infection-mediated resistance to transplantation tolerance","volume":"180","author":"Stapler","year":"2008","journal-title":"J Immunol"},{"key":"10.1111\/tri.12021-BIB0029|tri12021-cit-0029","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1097\/01.TP.0000164510.25625.70","article-title":"Short-term immunosuppression facilitates induction of mixed chimerism and tolerance after bone marrow transplantation without cytoreductive conditioning","volume":"80","author":"Blaha","year":"2005","journal-title":"Transplantation"},{"key":"10.1111\/tri.12021-BIB0030|tri12021-cit-0030","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1111\/j.1432-2277.2010.01120.x","article-title":"The role of natural killer T cells in costimulation blockade-based mixed chimerism","volume":"23","author":"Nierlich","year":"2010","journal-title":"Transpl Int"},{"key":"10.1111\/tri.12021-BIB0031|tri12021-cit-0031","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1097\/TP.0b013e3181bd7b3a","article-title":"Bortezomib can suppress activation of rapamycin-resistant memory T cells without affecting regulatory T-cell viability in non-human primates","volume":"88","author":"Kim","year":"2009","journal-title":"Transplantation"},{"key":"10.1111\/tri.12021-BIB0032|tri12021-cit-0032","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/j.1432-2277.2008.00802.x","article-title":"Inhibition of TNF-alpha reduces transplant arteriosclerosis in a murine aortic transplant model","volume":"22","author":"Wollin","year":"2009","journal-title":"Transpl Int"},{"key":"10.1111\/tri.12021-BIB0033|tri12021-cit-0033","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1517\/14728214.8.2.323","article-title":"Emerging therapies for graft-versus-host disease","volume":"8","author":"Jacobsohn","year":"2003","journal-title":"Expert Opin Emerg Drugs"},{"key":"10.1111\/tri.12021-BIB0034|tri12021-cit-0034","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1172\/JCI38482","article-title":"Anti-TNF immunotherapy reduces CD8+ T cell-mediated antimicrobial activity against Mycobacterium tuberculosis in humans","volume":"119","author":"Bruns","year":"2009","journal-title":"J Clin Invest"},{"key":"10.1111\/tri.12021-BIB0035|tri12021-cit-0035","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1111\/j.1600-6143.2006.01550.x","article-title":"Neutralizing IL-7 promotes long-term allograft survival induced by CD40\/CD40L costimulatory blockade","volume":"6","author":"Wang","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0036|tri12021-cit-0036","first-page":"A497","article-title":"Allograft tolerance induced by combined anti-LFA-1 and anti-ICAM-1 mAb is associated with shift from Th1 to Th2 cytokine expression in allograft","volume":"9","author":"Bucy","year":"1995","journal-title":"FASEB J"},{"key":"10.1111\/tri.12021-BIB0037|tri12021-cit-0037","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0966-3274(02)00014-X","article-title":"CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely","volume":"10","author":"Corbascio","year":"2002","journal-title":"Transpl Immunol"},{"key":"10.1111\/tri.12021-BIB0038|tri12021-cit-0038","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1038\/nri2546","article-title":"Immunoregulatory functions of mTOR inhibition","volume":"9","author":"Thomson","year":"2009","journal-title":"Nat Rev Immunol"},{"key":"10.1111\/tri.12021-BIB0039|tri12021-cit-0039","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1182\/blood-2003-08-2642","article-title":"Mechanisms of early peripheral CD4 T cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion, but not regulatory cells","volume":"103","author":"Kurtz","year":"2004","journal-title":"Blood"},{"key":"10.1111\/tri.12021-BIB0040|tri12021-cit-0040","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF01719234","article-title":"The genetic basis of negative selection of Tcrb-V11+ T cells","volume":"33","author":"Tomonari","year":"1991","journal-title":"Immunogenetics"},{"key":"10.1111\/tri.12021-BIB0041|tri12021-cit-0041","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1084\/jem.169.4.1405","article-title":"The MHC molecule I-E is necessary but not sufficient for the clonal deletion of VB11 bearing T cells","volume":"169","author":"Bill","year":"1989","journal-title":"J Exp Med"},{"key":"10.1111\/tri.12021-BIB0042|tri12021-cit-0042","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/349531a0","article-title":"Genes encoding ligands for deletion of Vb11 T cells cosegregate with mammary tumour virus genomes","volume":"349","author":"Dyson","year":"1991","journal-title":"Nature"},{"key":"10.1111\/tri.12021-BIB0043|tri12021-cit-0043","doi-asserted-by":"crossref","first-page":"8789","DOI":"10.1073\/pnas.94.16.8789","article-title":"CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates","volume":"94","author":"Kirk","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1111\/tri.12021-BIB0044|tri12021-cit-0044","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1600-6143.2005.00749.x","article-title":"Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties","volume":"5","author":"Larsen","year":"2005","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0045|tri12021-cit-0045","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1056\/NEJMoa050085","article-title":"Costimulation blockade with belatacept in renal transplantation","volume":"353","author":"Vincenti","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1111\/tri.12021-BIB0046|tri12021-cit-0046","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1038\/nm.1993","article-title":"Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates","volume":"15","author":"Weaver","year":"2009","journal-title":"Nat Med"},{"key":"10.1111\/tri.12021-BIB0047|tri12021-cit-0047","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1600-065X.2009.00776.x","article-title":"Translating costimulation blockade to the clinic: lessons learned from three pathways","volume":"229","author":"Ford","year":"2009","journal-title":"Immunol Rev"},{"key":"10.1111\/tri.12021-BIB0048|tri12021-cit-0048","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1600-6143.2005.01158.x","article-title":"LFA-1 (CD11a) as a therapeutic target","volume":"6","author":"Nicolls","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0049|tri12021-cit-0049","doi-asserted-by":"crossref","first-page":"7025","DOI":"10.4049\/jimmunol.173.11.7025","article-title":"Combinations of anti-LFA-1, everolimus, anti-CD40 ligand, and allogeneic bone marrow induce central transplantation tolerance through hemopoietic chimerism, including protection from chronic heart allograft rejection","volume":"173","author":"Metzler","year":"2004","journal-title":"J Immunol"},{"key":"10.1111\/tri.12021-BIB0050|tri12021-cit-0050","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1600-6143.2011.03762.x","article-title":"Integrin antagonists prevent costimulatory blockade-resistant transplant rejection by CD8(+) memory T cells","volume":"12","author":"Kitchens","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0051|tri12021-cit-0051","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1111\/j.1600-6143.2011.03492.x","article-title":"LFA-1 antagonism inhibits early infiltration of endogenous memory CD8 T cells into cardiac allografts and donor-reactive T cell priming","volume":"11","author":"Setoguchi","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0052|tri12021-cit-0052","doi-asserted-by":"crossref","first-page":"4520","DOI":"10.1172\/JCI43895","article-title":"LFA-1-specific therapy prolongs allograft survival in rhesus macaques","volume":"120","author":"Badell","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1111\/tri.12021-BIB0053|tri12021-cit-0053","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1056\/NEJMoa030002","article-title":"A novel targeted T-cell modulator, efalizumab, for plaque psoriasis","volume":"349","author":"Lebwohl","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1111\/tri.12021-BIB0054|tri12021-cit-0054","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1111\/j.1600-6143.2007.01845.x","article-title":"A phase I\/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation","volume":"7","author":"Vincenti","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0055|tri12021-cit-0055","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1111\/j.1600-6143.2010.03212.x","article-title":"Experience with a novel efalizumab-based immunosuppressive regimen to facilitate single donor islet cell transplantation","volume":"10","author":"Turgeon","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0056|tri12021-cit-0056","doi-asserted-by":"crossref","first-page":"5851","DOI":"10.1182\/blood-2011-04-347252","article-title":"LFA-1 blockade induces effector and regulatory T-cell enrichment in lymph nodes and synergizes with CTLA-4Ig to inhibit effector function","volume":"118","author":"Reisman","year":"2011","journal-title":"Blood"},{"key":"10.1111\/tri.12021-BIB0057|tri12021-cit-0057","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1097\/TP.0b013e31824e75d7","article-title":"Combined costimulatory and leukocyte functional antigen-1 blockade prevents transplant rejection mediated by heterologous immune memory alloresponses","volume":"93","author":"Kitchens","year":"2012","journal-title":"Transplantation"},{"key":"10.1111\/tri.12021-BIB0058|tri12021-cit-0058","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/nri2858","article-title":"Antigen-presenting cell function in the tolerogenic liver environment","volume":"10","author":"Thomson","year":"2010","journal-title":"Nat Rev"},{"key":"10.1111\/tri.12021-BIB0059|tri12021-cit-0059","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/nature08155","article-title":"mTOR regulates memory CD8 T-cell differentiation","volume":"460","author":"Araki","year":"2009","journal-title":"Nature"},{"key":"10.1111\/tri.12021-BIB0060|tri12021-cit-0060","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.4049\/jimmunol.1001176","article-title":"Cutting edge: rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses","volume":"185","author":"Ferrer","year":"2010","journal-title":"J Immunol"},{"key":"10.1111\/tri.12021-BIB0061|tri12021-cit-0061","doi-asserted-by":"crossref","first-page":"4743","DOI":"10.1182\/blood-2004-10-3932","article-title":"Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells","volume":"105","author":"Battaglia","year":"2005","journal-title":"Blood"},{"key":"10.1111\/tri.12021-BIB0062|tri12021-cit-0062","doi-asserted-by":"crossref","first-page":"3400","DOI":"10.1182\/blood-2002-03-0872","article-title":"Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions","volume":"100","author":"Taylor","year":"2002","journal-title":"Blood"},{"key":"10.1111\/tri.12021-BIB0063|tri12021-cit-0063","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1600-6143.2010.03018.x","article-title":"Treg-therapy allows mixed chimerism and transplantation tolerance without cytoreductive conditioning","volume":"10","author":"Pilat","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0064|tri12021-cit-0064","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1111\/j.1600-6143.2011.03963.x","article-title":"Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus","volume":"12","author":"Singh","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1111\/tri.12021-BIB0065|tri12021-cit-0065","doi-asserted-by":"crossref","first-page":"3991","DOI":"10.1182\/blood-2002-09-2859","article-title":"Antigen-primed CD8+ T cells can mediate resistance, preventing allogeneic marrow engraftment in the simultaneous absence of perforin-, CD95L-, TNFR1-, and TRAIL-dependent killing","volume":"101","author":"Komatsu","year":"2003","journal-title":"Blood"},{"key":"10.1111\/tri.12021-BIB0066|tri12021-cit-0066","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.bbmt.2005.05.006","article-title":"Effector cells derived from host CD8 memory T cells mediate rapid resistance against minor histocompatibility antigen-mismatched allogeneic marrow grafts without participation of perforin, Fas ligand, and the simultaneous inhibition of 3 tumor necrosis factor family effector pathways","volume":"11","author":"Zimmerman","year":"2005","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1111\/tri.12021-BIB0067|tri12021-cit-0067","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.bbmt.2003.12.305","article-title":"Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation","volume":"10","author":"Cutler","year":"2004","journal-title":"Biol Blood Marrow Transplant"}],"container-title":["Transplant International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Ftri.12021","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/tri.12021\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T18:39:43Z","timestamp":1641062383000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/tri.12021"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,13]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"URL":"https:\/\/doi.org\/10.1111\/tri.12021","relation":{},"ISSN":["0934-0874"],"issn-type":[{"value":"0934-0874","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12,13]]}}}