{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T06:30:18Z","timestamp":1781850618884,"version":"3.54.5"},"reference-count":10,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["vaajournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1111\/vaa.12278","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T14:16:50Z","timestamp":1433427410000},"page":"209-214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Transnasal administration of a combination of dexmedetomidine, midazolam and butorphanol produces deep sedation in New Zealand White rabbits"],"prefix":"10.1016","volume":"43","author":[{"given":"Bruna","family":"Santangelo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana","family":"Micieli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Mozzillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana","family":"Reynaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Marino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Auletta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo","family":"Vesce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/vaa.12278_bib1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.2460\/ajvr.73.4.539","article-title":"Bioavailability of a novel midazolam gel after intranasal administration in dogs","volume":"73","author":"Eagleson","year":"2012","journal-title":"Am J Vet Res"},{"key":"10.1111\/vaa.12278_bib2","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1046\/j.1467-2987.2001.00058.x","article-title":"Anaesthesia with ketamine\/medetomidine in the rabbit: influence of route of administration and the effect of combination with Butorphanol","volume":"29","author":"Hedenqvist","year":"2002","journal-title":"Vet Anaesth Analg"},{"key":"10.1111\/vaa.12278_bib3","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/1746-6148-9-21","article-title":"Continuous intravenous anaesthesia with sufentanil and midazolam in medetomidine premedicated New Zealand White rabbits","volume":"9","author":"Hedenqvist","year":"2013","journal-title":"BMC Vet Res"},{"key":"10.1111\/vaa.12278_bib4","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/j.1467-2995.2005.00242.x","article-title":"Comparative study of three intramuscular anaesthetic combinations (medetomidine\/ketamine, medetomidine\/fentanyl\/midazolam and xylazine\/ketamine) in rabbits","volume":"32","author":"Henke","year":"2005","journal-title":"Vet Anaesth Analg"},{"key":"10.1111\/vaa.12278_bib5","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1007\/s00134-002-1338-y","article-title":"The effects of dexmedetomidine on the ventilatory response to hypercapnia in rabbits","volume":"28","author":"Nishida","year":"2002","journal-title":"Intensive Care Med"},{"key":"10.1111\/vaa.12278_bib6","doi-asserted-by":"crossref","first-page":"541","DOI":"10.2460\/ajvr.1991.53.04.541","article-title":"Pharmacokinetics of butorphanol tartrate in rabbits","volume":"53","author":"Portnoy","year":"1992","journal-title":"Am J Vet Res"},{"key":"10.1111\/vaa.12278_bib7","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1046\/j.1365-2885.2002.00382.x","article-title":"Some factors influencing the level of clinical sedation induced by medetomidine in rabbits","volume":"25","author":"Raekallio","year":"2002","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1111\/vaa.12278_bib8","first-page":"159","article-title":"Efficacy of the intranasal route for administration of anesthetic agents to adult rabbits","volume":"44","author":"Robertson","year":"1994","journal-title":"Lab Anim Sci"},{"key":"10.1111\/vaa.12278_bib9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.5818\/1529-9651-22.3.91","article-title":"The efficacy of intranasal administration of dexmedetomidine and ketamine to Yellow-Bellied Sliders (Trachemys scripta scripta)","volume":"22","author":"Schnellbacher","year":"2012","journal-title":"J Herpetol Med Surg"},{"key":"10.1111\/vaa.12278_bib10","first-page":"205","article-title":"Respiratory rates and arterial blood-gas tensions in healthy rabbits given buprenorphine, butorphanol, midazolam, or their combinations","volume":"50","author":"Schroeder","year":"2011","journal-title":"J Am Assoc Lab Anim Sci"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298716300605?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298716300605?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T02:49:35Z","timestamp":1761446975000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467298716300605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S1467298716300605"],"URL":"https:\/\/doi.org\/10.1111\/vaa.12278","relation":{},"ISSN":["1467-2987"],"issn-type":[{"value":"1467-2987","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transnasal administration of a combination of dexmedetomidine, midazolam and butorphanol produces deep sedation in New Zealand White rabbits","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/vaa.12278","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}