{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T06:25:25Z","timestamp":1790058325246,"version":"4.0.1"},"reference-count":10,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["vaajournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Anaesthesia and Analgesia"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1111\/vaa.12316","type":"journal-article","created":{"date-parts":[[2015,10,19]],"date-time":"2015-10-19T11:28:43Z","timestamp":1445254123000},"page":"189-194","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Preliminary investigation comparing a detomidine continuous rate infusion combined with either morphine or buprenorphine for standing sedation in horses"],"prefix":"10.1016","volume":"43","author":[{"given":"Joanna J","family":"Potter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D","family":"MacFarlane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma J","family":"Love","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry","family":"Tremaine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Polly M","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna C","family":"Murrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/vaa.12316_bib1","doi-asserted-by":"crossref","first-page":"992","DOI":"10.2460\/ajvr.67.6.992","article-title":"Evaluation of the effects of the opioid agonist morphine on gastrointestinal tract function in horses","volume":"67","author":"Boscan","year":"2006","journal-title":"Am J Vet Res"},{"key":"10.1111\/vaa.12316_bib2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.2460\/ajvr.68.3.246","article-title":"Effects of buprenorphine on nociception and spontaneous locomotor activity in horses","volume":"68","author":"Carregaro","year":"2007","journal-title":"Am J Vet Res"},{"key":"10.1111\/vaa.12316_bib3","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1365-2885.2011.01284.x","article-title":"Pharmacokinetics of intravenous and intramuscular buprenorphine in the horse","volume":"35","author":"Davis","year":"2011","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1111\/vaa.12316_bib4","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/j.1365-2885.1992.tb01007.x","article-title":"A comparison of the sedative effects of three \u03b1 2-adrenoceptor agonists (romifidine, detomidine and xylazine) in the horse","volume":"15","author":"England","year":"1992","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1111\/vaa.12316_bib5","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/jvp.12098","article-title":"Preliminary pharmacokinetics of morphine and its major metabolites following intravenous administration of four doses to horses","volume":"37","author":"Knych","year":"2014","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1111\/vaa.12316_bib6","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1136\/vr.101440","article-title":"Postcastration analgesia in ponies using buprenorphine hydrochloride","volume":"172","author":"Love","year":"2013","journal-title":"Vet Rec"},{"key":"10.1111\/vaa.12316_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/vaa.12165","article-title":"Pharmacokinetic\u2013pharmacodynamic modelling of intravenous buprenorphine in conscious horses","volume":"42","author":"Love","year":"2015","journal-title":"Vet Anaesth Analg"},{"key":"10.1111\/vaa.12316_bib8","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/vaa.12238","article-title":"Detomidine and the combination of detomidine and MK-467 a peripheral alpha-2 adrenoceptor antagonist, as premedication in horses anaesthetised with isoflurane","volume":"42","author":"Pakkanen","year":"2015","journal-title":"Vet Anaesth Analg"},{"key":"10.1111\/vaa.12316_bib9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.2746\/042516408X342984","article-title":"Behavioural and cardiorespiratory effects of a constant rate infusion of medetomidine and morphine for sedation during standing laparoscopy in horses","volume":"41","author":"Solano","year":"2009","journal-title":"Equine Vet J"},{"key":"10.1111\/vaa.12316_bib10","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1046\/j.1467-2995.2003.00097.x","article-title":"Hormonal, metabolic and physiological effects of laparoscopic surgery using a detomidine\u2013buprenorphine combination in standing horses","volume":"30","author":"Van Dijk","year":"2003","journal-title":"Vet Anaesth Analg"}],"container-title":["Veterinary Anaesthesia and Analgesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298716300563?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1467298716300563?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T02:49:12Z","timestamp":1761446952000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1467298716300563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["S1467298716300563"],"URL":"https:\/\/doi.org\/10.1111\/vaa.12316","relation":{},"ISSN":["1467-2987"],"issn-type":[{"value":"1467-2987","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preliminary investigation comparing a detomidine continuous rate infusion combined with either morphine or buprenorphine for standing sedation in horses","name":"articletitle","label":"Article Title"},{"value":"Veterinary Anaesthesia and Analgesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/vaa.12316","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Association of Veterinary Anaesthetists and American College of Veterinary Anesthesia and Analgesia. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}