{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T11:32:46Z","timestamp":1740137566452,"version":"3.37.3"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Vet Comparative Oncology"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>The objective of this prospective study was to evaluate agreement and reliability of calliper\u2010based measurements of locally invasive subcutaneous malignant tumours in dogs. Four raters measured the longest diameter of 12 subcutaneous tumours (7 soft tissue sarcomas and 5 mast cell tumours) from 11 client\u2010owned dogs during 3 randomized, blinded measurement trials, both pre\u2010 and post\u2010sedation. Inter\u2010 and intra\u2010rater reliability was evaluated using intra\u2010class correlation coefficient (ICC) and agreement was evaluated using Bland\u2010Altman plots. Inter\u2010 and intra\u2010rater reliability was good (ICC range of 0.8694\u20100.89520) and excellent (ICC range of 0.9720\u20100.9966), respectively. For agreement calculations, an a priori clinically relevant limit of agreement of 10 mm was set. Inter\u2010 and intra\u2010rater agreement was unacceptable with inter\u2010rater limits of agreement ranging from 15.9 to 55.6 mm and intra\u2010rater limit of agreement ranging from 11.9 to 28.1 mm. Review of the measurement trial photographs revealed that calliper orientation changes were frequent, occurring in 9\/12 (75%) and 8\/12 (67%) pre\u2010 and post\u2010sedation cases. No significant correlation was found between inter\u2010rater measurement standard deviations and calliper orientation changes or dog body condition score. These findings suggest veterinarians may have poor agreement in determining the gross edge of tumours, which is expected to introduce bias and inconsistency in tumour staging, assessing response to therapy, and surgical margin planning. Due to the potential consequences for veterinary cancer patients, future studies are needed to validate the present findings.<\/jats:p>","DOI":"10.1111\/vco.12394","type":"journal-article","created":{"date-parts":[[2018,3,2]],"date-time":"2018-03-02T04:38:36Z","timestamp":1519965516000},"page":"392-398","source":"Crossref","is-referenced-by-count":6,"title":["Inter\u2010 and intra\u2010rater reliability and agreement in determining subcutaneous tumour margins in dogs"],"prefix":"10.1111","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9382-3334","authenticated-orcid":false,"given":"B.","family":"Ranganathan","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine Oregon State University Corvallis Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0556-4409","authenticated-orcid":false,"given":"M.","family":"Milovancev","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine Oregon State University Corvallis Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0900-0851","authenticated-orcid":false,"given":"H.","family":"Leeper","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine Oregon State University Corvallis Oregon"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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