{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T20:41:00Z","timestamp":1772052060834,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:00:00Z","timestamp":1750204800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Comparative Oncology"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The treatment of choice for canine alimentary tract neoplasms is surgical excision, but it can sometimes be difficult to achieve wide margins due to neoplasm location, size, or distribution. Optical coherence tomography (OCT) is a rapid, noninvasive imaging modality that uses light to characterise tissue microstructure to allow identification of different tissue types. Spectral domain (SD)\u2010OCT allows for differentiation based on the total light intensity reflected from the tissue. Polarisation sensitive (PS)\u2010OCT detects the polarisation state of light reflected by the tissues. The polarisation properties are phase retardation, degree of polarisation uniformity (DOPU), and optical axis. Our objective was to qualitatively characterise different tissues at the excision sites of alimentary tract neoplasms using OCT. Oral, liver, and other alimentary tumours including stomach, intestine, and pancreas were imaged. Samples were then fixed in formalin, paraffin embedded and stained with haematoxylin and eosin. OCT images and histology slides were compared, and the tissues were qualitatively described by a single investigator. We hypothesized that PS\u2010OCT imaging would provide distinguishing characteristics of tissue appearances that could be used in the future to train observers or artificial intelligence to identify incomplete margins. Our results showed that alimentary tract tumours have disorganised microstructures on SD\u2010OCT and PS\u2010OCT DOPU, and PS\u2010OCT phase retardation and optical axis values that differ from normal tissues. Thus, these characteristics can be used to differentiate neoplastic and normal tissues at surgical margins.<\/jats:p>","DOI":"10.1111\/vco.70001","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T03:21:11Z","timestamp":1750216871000},"page":"486-492","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Polarisation Sensitive Optical Coherence Tomography Image Characteristics for Gastrointestinal Tumours and Normal Tissues at Surgical Margins in Dogs"],"prefix":"10.1111","volume":"23","author":[{"given":"Hannah L.","family":"Weaver","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine The Ohio State University  Columbus Ohio USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8332-9706","authenticated-orcid":false,"given":"Gabrielle 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