{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T04:22:25Z","timestamp":1794198145715,"version":"4.8.0"},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T00:00:00Z","timestamp":1783555200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Vet Comparative Oncology"],"published-print":{"date-parts":[[2026,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Inking of canine skin tumours facilitates histopathological margin assessment. While traditional dab application is standard practice, aerosolised (spray) application may offer practical advantages. The objective of this study was to determine if aerosolised ink application provides comparable margin coverage to traditional dab methods and to compare time of application and volume of ink used. A blinded, randomised study on 19 canine skin tumours was performed. Each tumour was sectioned into two halves and one half randomly assigned a method (dab or spray) and ink colour (black or blue) with the other half receiving the alternative method and colour. Margin coverage (percentage of margin covered by ink), application time and ink volume were measured. Spray application was non\u2010inferior to dab with respect to margin coverage, with mean margin coverage estimated as being 0.25 to 0.41 percentage points greater and lower limits of 95% confidence intervals \u22120.72 and \u22120.35 percentage points, respectively. Spray application was estimated as being 38\u2009s faster on average (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) but used approximately 0.5\u2009mL more ink (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). These findings suggest that aerosolised inking provides comparable margin coverage while reducing application time; however, ink placement fidelity was not assessed, and further evaluation is warranted to confirm full clinical equivalence.\n                  <\/jats:p>","DOI":"10.1111\/vco.70089","type":"journal-article","created":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T10:51:20Z","timestamp":1783594280000},"page":"726-731","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Aerosolised and Traditional Tumour Margin Inking: A Prospective Blinded Histopathological Review in Canine Skin Tumours"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4897-1913","authenticated-orcid":false,"given":"Kaida L.","family":"Wouters","sequence":"first","affiliation":[{"name":"Advanced Vetcare, Vetnostics Pathology  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam R.","family":"Snelling","sequence":"additional","affiliation":[{"name":"Advanced Vetcare, Vetnostics Pathology  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8926-5942","authenticated-orcid":false,"given":"John M.","family":"Morton","sequence":"additional","affiliation":[{"name":"Advanced Vetcare, Vetnostics Pathology  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0250-5849","authenticated-orcid":false,"given":"Simon","family":"Stokes","sequence":"additional","affiliation":[{"name":"Advanced Vetcare, Vetnostics Pathology  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,9]]},"reference":[{"issue":"1","key":"e_1_2_9_2_1","first-page":"55","article-title":"Determining Adequate Surgical Margins for Resection of Cutaneous Neoplasms","volume":"49","author":"Milovancev M.","year":"2019","journal-title":"Veterinary Clinics of North America: Small Animal Practice"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300985810389316"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/vco.12284"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u2010950X.2013.12069.x"},{"key":"e_1_2_9_6_1","volume-title":"Fractional Outcome Regression","author":"StataCorp LLC","year":"2025"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11121\u2010016\u20100643\u20106"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.87802"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12328"}],"container-title":["Veterinary and Comparative Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vco.70089","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vco.70089","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vco.70089","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T03:54:08Z","timestamp":1794196448000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vco.70089"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,9]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["10.1111\/vco.70089"],"URL":"https:\/\/doi.org\/10.1111\/vco.70089","archive":["Portico"],"relation":{},"ISSN":["1476-5810","1476-5829"],"issn-type":[{"value":"1476-5810","type":"print"},{"value":"1476-5829","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,9]]},"assertion":[{"value":"2025-10-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}