{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:24:22Z","timestamp":1787016262850,"version":"build-2736575974"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,31]],"date-time":"2012-12-31T00:00:00Z","timestamp":1356912000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2013,3]]},"abstract":"\n Background<\/jats:title>\n \n In cats, mastocytemia is considered to be confined to animals with mast cell tumors (\n MCT<\/jats:styled-content>\n ), whereas in dogs it is associated with diverse diseases.\n <\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n The objective of this retrospective study was to investigate the diagnostic and prognostic significance of mastocytemia in cats.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n All blood smears and buffy coat (\n BC<\/jats:styled-content>\n ) smears on which mast cells were identified over a 6\u2010year period were retrospectively reviewed and mast cells counted. Mastocytemic cats were classified based on their clinical diagnosis.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Mastocytemia was identified on 40 blood smears and 13\n BC<\/jats:styled-content>\n smears from 33 cats. The incidence of mastocytemia detected in cats during routine\n CBC<\/jats:styled-content>\n s was 0.33% (40\/12,116\n CBC<\/jats:styled-content>\n s). Twenty\u2010two of 33 mastocytemic cats (67%) had visceral (\n n<\/jats:italic>\n \u00a0=\u00a017) or cutaneous\n MCT<\/jats:styled-content>\n (\n n<\/jats:italic>\n \u00a0=\u00a07), including 2 that had concurrent visceral and cutaneous involvement. In 3 additional cases (9%), visceral\n MCT<\/jats:styled-content>\n was clinically suspected, but no cytologic or histopathologic evaluation of visceral organs was performed.\n MCT<\/jats:styled-content>\n was excluded in 3 of 33 mastocytemic cats (9%) with a final diagnosis of lymphoid neoplasia (\n n<\/jats:italic>\n \u00a0=\u00a02) and multiorgan hemangiosarcoma (\n n<\/jats:italic>\n \u00a0=\u00a01). Five additional animals (15%) had a diagnosis other than\n MCT<\/jats:styled-content>\n , including lymphoma (\n n<\/jats:italic>\n \u00a0=\u00a02) and chronic renal failure (\n n<\/jats:italic>\n \u00a0=\u00a03), but no cytologic or histopathologic evaluation of the spleen was performed. Blood smears from cats with confirmed\n MCT<\/jats:styled-content>\n had 1\u2013113 mast cells per smear, whereas cats in which\n MCT<\/jats:styled-content>\n was excluded had 1\u20132 mast cells per smear.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Data confirm that mastocytemia is rare and most commonly found in cats with visceral\n MCT<\/jats:styled-content>\n ; however, rare circulating mast cells may also be seen with neoplasms other than\n MCT<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/vcp.12021","type":"journal-article","created":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T15:20:16Z","timestamp":1357053616000},"page":"4-10","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Significance of mastocytemia in cats"],"prefix":"10.1111","volume":"42","author":[{"given":"Martina","family":"Piviani","sequence":"first","affiliation":[{"name":"Department of Pathobiology School of Veterinary Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel M.","family":"Walton","sequence":"additional","affiliation":[{"name":"Department of Pathobiology School of Veterinary Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reema T.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Pathobiology School of Veterinary Medicine University of Pennsylvania Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,31]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2010.08.003"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.231.11.1685"},{"key":"e_1_2_5_4_1","first-page":"420","volume-title":"Small Animal Clinical Oncology","author":"Thamm 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