{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T13:03:59Z","timestamp":1769346239405,"version":"3.49.0"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T00:00:00Z","timestamp":1397433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Markedly overweight people can develop progressive proteinuria and kidney failure secondary to obesity\u2010related glomerulopathy (<jats:styled-content style=\"fixed-case\">ORG<\/jats:styled-content>). Glomerular lesions in dogs with experimentally induced obesity are similar to those in people with <jats:styled-content style=\"fixed-case\">ORG<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to evaluate if urine protein and albumin excretion is greater in overweight and obese dogs than in dogs of ideal body condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Client\u2010owned dogs were screened for underlying health conditions. These dogs were assigned a body condition score (<jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content>) using a 9\u2010point scoring system. Dogs with a <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> of \u2265\u00a06 were classified as being overweight\/obese, and dogs with a <jats:styled-content style=\"fixed-case\">BCS<\/jats:styled-content> of 4 or 5 were classified as being of ideal body weight. The urine protein:creatinine ratio (<jats:styled-content style=\"fixed-case\">UPC<\/jats:styled-content>) and urine albumin:creatinine ratio (<jats:styled-content style=\"fixed-case\">UAC<\/jats:styled-content>) were then determined, and compared between 20 overweight\/obese dogs and 22 ideal body weight control dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Median UPC (0.04 [range, 0.01\u20130.14; interquartile range, 0.07]) and UAC (0.41 [0\u201310.39; 3.21]) of overweight\/obese dogs were not significantly different from median <jats:styled-content style=\"fixed-case\">UPC<\/jats:styled-content> (0.04 [0.01\u20130.32; 0.07]) and <jats:styled-content style=\"fixed-case\">UAC<\/jats:styled-content> (0.18 [0\u20137.04; 1.75]) in ideal body weight dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Clinicopathologic abnormalities consistent with <jats:styled-content style=\"fixed-case\">ORG<\/jats:styled-content> were absent from overweight\/obese dogs in this study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vcp.12139","type":"journal-article","created":{"date-parts":[[2014,4,14]],"date-time":"2014-04-14T16:51:51Z","timestamp":1397494311000},"page":"255-260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Association between excess body weight and urine protein concentration in healthy dogs"],"prefix":"10.1111","volume":"43","author":[{"given":"Karen M.","family":"Tefft","sequence":"first","affiliation":[{"name":"Department of Companion Animals Atlantic Veterinary College University of Prince Edward Island Charlottetown PEI Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darcy H.","family":"Shaw","sequence":"additional","affiliation":[{"name":"Department of Companion Animals Atlantic Veterinary College University of Prince Edward Island Charlottetown PEI Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherri L.","family":"Ihle","sequence":"additional","affiliation":[{"name":"Department of Companion Animals Atlantic Veterinary College University of Prince Edward Island Charlottetown PEI Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shelley A.","family":"Burton","sequence":"additional","affiliation":[{"name":"Department of Pathology and Microbiology Atlantic Veterinary College University of Prince Edward Island Charlottetown PEI Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LeeAnn","family":"Pack","sequence":"additional","affiliation":[{"name":"Department of Companion Animals Atlantic Veterinary College University of Prince Edward Island Charlottetown PEI Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,4,14]]},"reference":[{"key":"e_1_2_3_2_1","first-page":"177","article-title":"Prevalence and 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