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On physical examination, an abdominal mass was palpated. The abdominal mass was aspirated and cytologically diagnosed as a neuroendocrine tumor, suspected to be a pheochromocytoma. Laboratory examination revealed a mild anemia and thrombocytopenia, markedly elevated<jats:styled-content style=\"fixed-case\">ATP<\/jats:styled-content>and<jats:styled-content style=\"fixed-case\">ALP<\/jats:styled-content>activities, and moderate hypercalcemia. A low\u2010dose dexamethasone suppression test and endogenous adrenocorticotropic hormone (ACTH) concentration were compatible with pituitary hyperadrenocorticism. On urinalysis, proteinuria was noted as well as a high urine metanephrine\/creatinine ratio, consistent with a diagnosis of pheochromocytoma. The dog was treated with supportive care and euthanized 6 months later due to decreasing quality of life. On necropsy, an extra\u2010adrenal pheochromocytoma (paraganglioma) was diagnosed in the caudal abdomen, and a pituitary adenoma and an osteosarcoma of the right distal radius were confirmed.<\/jats:p>","DOI":"10.1111\/vcp.12376","type":"journal-article","created":{"date-parts":[[2016,7,18]],"date-time":"2016-07-18T14:07:23Z","timestamp":1468850843000},"page":"484-489","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Paraganglioma, pituitary adenoma, and osteosarcoma in a dog"],"prefix":"10.1111","volume":"45","author":[{"given":"Cecilia","family":"Robat","sequence":"first","affiliation":[{"name":"UW Madison School of Veterinary Medicine Madison WI USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Houseright","sequence":"additional","affiliation":[{"name":"UW Madison School of Veterinary Medicine Madison WI 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