{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T14:13:45Z","timestamp":1783952025433,"version":"3.55.0"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T00:00:00Z","timestamp":1485388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Pancreatic abnormalities during canine parvovirus (<jats:styled-content style=\"fixed-case\">CPV<\/jats:styled-content>) enteritis have not been studied prospectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this study was to evaluate the diagnostic significance of canine serum pancreas\u2010specific lipase (Spec<jats:styled-content style=\"fixed-case\">cPL<\/jats:styled-content>) concentration in dogs with<jats:styled-content style=\"fixed-case\">CPV<\/jats:styled-content>enteritis for the presence of acute pancreatitis (<jats:styled-content style=\"fixed-case\">AP<\/jats:styled-content>). Puppies with naturally occurring<jats:styled-content style=\"fixed-case\">CPV<\/jats:styled-content>enteritis were recruited and prospectively allocated into 2 groups according to normal or increased serum Spec<jats:styled-content style=\"fixed-case\">cPL<\/jats:styled-content>concentration. Clinical signs, laboratory findings, and pancreas\u2010associated variables were compared between groups, and the impact of possible<jats:styled-content style=\"fixed-case\">AP<\/jats:styled-content>on disease course, duration of hospitalization, and outcome was assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Serum Spec<jats:styled-content style=\"fixed-case\">cPL<\/jats:styled-content>concentration in 35 puppies was above the upper limit of the<jats:styled-content style=\"fixed-case\">RI<\/jats:styled-content>in 17\/35 (48.6%) dogs (Group A) and within the<jats:styled-content style=\"fixed-case\">RI<\/jats:styled-content>in 18 dogs (Group B). An increased serum lipase activity was present in 29\/35 (82.9%) dogs, and Group A dogs had a higher serum lipase activity than Group B (<jats:italic>P<\/jats:italic>= .006). Serum Spec<jats:styled-content style=\"fixed-case\">cPL<\/jats:styled-content>in Group A dogs was positively correlated with serum lipase activity at the day of presentation (<jats:italic>r<\/jats:italic>= .667;<jats:italic>P =<\/jats:italic>.003) and day of discharge (<jats:italic>r<\/jats:italic>= .628;<jats:italic>P =<\/jats:italic>.007). No statistically significant difference was found between groups (<jats:italic>P<\/jats:italic>= .233) for the presence of systemic inflammatory response syndrome (<jats:styled-content style=\"fixed-case\">SIRS<\/jats:styled-content>) (6\/17 or 35.3% dogs Group A, and 8\/18 or 44.4% dogs Group B), the disease course, duration of hospitalization, or outcome between groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Increased serum Spec<jats:styled-content style=\"fixed-case\">cPL<\/jats:styled-content>is relatively common in dogs with<jats:styled-content style=\"fixed-case\">CPV<\/jats:styled-content>enteritis. However, such increases do not seem to correlate with the outcome of disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vcp.12447","type":"journal-article","created":{"date-parts":[[2017,1,26]],"date-time":"2017-01-26T14:16:42Z","timestamp":1485440202000},"page":"111-119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prevalence of increased canine pancreas\u2010specific lipase concentrations in young dogs with parvovirus enteritis"],"prefix":"10.1111","volume":"46","author":[{"given":"Irida V.","family":"Kalli","sequence":"first","affiliation":[{"name":"Companion Animal Clinic School of Veterinary Medicine Faculty of Health Sciences Aristotle University of Thessaloniki Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina K.","family":"Adamama\u2010Moraitou","sequence":"additional","affiliation":[{"name":"Companion Animal Clinic School of Veterinary Medicine Faculty of Health 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