{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T22:45:17Z","timestamp":1778193917891,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,3,13]],"date-time":"2017-03-13T00:00:00Z","timestamp":1489363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A neutered male Mexican Hairless dog was presented for generalized weight loss and weakness. Initial laboratory testing and diagnostic imaging revealed thrombocytopenia and an interstitial to miliary lung pattern affecting all lung fields. Mild joint effusion was found on physical examination affecting the stifle, tarsal, carpal, and elbow joints. Examination of synovial fluid demonstrated an inflammatory polyarthropathy in 3 joints. Cytocentrifuged and direct preparations of the bronchoalveolar lavage (<jats:styled-content style=\"fixed-case\">BAL<\/jats:styled-content>) fluid sample were made and cells consistent with lupus erythematosus (<jats:styled-content style=\"fixed-case\">LE<\/jats:styled-content>) cells and ragocytes were found. Based on these findings, the anti\u2010nuclear antibody (<jats:styled-content style=\"fixed-case\">ANA<\/jats:styled-content>) titer was determined as 1:640. A clinical diagnosis of systemic LE was made based on the satisfaction of 2 major criteria (thrombocytopenia and inflammatory polyarthritis), 4 minor criteria (central nervous system signs, lymphadenopathy, fever of unknown origin, and pleuritis), positive <jats:styled-content style=\"fixed-case\">ANA<\/jats:styled-content> titer, and the identification of presumed <jats:styled-content style=\"fixed-case\">LE<\/jats:styled-content> cells in <jats:styled-content style=\"fixed-case\">BAL<\/jats:styled-content> fluid. This case report highlights a novel finding of <jats:styled-content style=\"fixed-case\">LE<\/jats:styled-content> cells in respiratory secretions and provides a review of diagnostic criteria of systemic LE.<\/jats:p>","DOI":"10.1111\/vcp.12471","type":"journal-article","created":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T18:13:48Z","timestamp":1489515228000},"page":"354-359","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Presumed lupus erythematosus cells identified in bronchoalveolar lavage fluid from a Mexican Hairless dog"],"prefix":"10.1111","volume":"46","author":[{"given":"Laura J.","family":"Black","sequence":"first","affiliation":[{"name":"Department of Physiological Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley C.","family":"Hechler","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maura E.","family":"Duffy","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah S.K.","family":"Beatty","sequence":"additional","affiliation":[{"name":"Department of Physiological Sciences College of Veterinary Medicine University of Florida Gainesville FL USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,13]]},"reference":[{"key":"e_1_2_2_2_1","first-page":"783","volume-title":"Textbook of Veterinary Internal Medicine","author":"Stone M","year":"2009"},{"key":"e_1_2_2_3_1","volume-title":"Pathologic Basis of Veterinary Disease","author":"Zachary JF","year":"2012"},{"key":"e_1_2_2_4_1","volume-title":"Robbins and Cotran Pathologic Basis of Disease","author":"Kumar V","year":"2015"},{"key":"e_1_2_2_5_1","first-page":"383","volume-title":"Schalm's Veterinary Hematology","author":"Chabanne L","year":"2010"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-165X.2010.00222.x"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.12232"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780251101"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2427(99)00059-8"},{"key":"e_1_2_2_10_1","first-page":"7","article-title":"Systemic lupus erythematosus","volume":"7","author":"Berent A","year":"2005","journal-title":"Compend Stand Care. 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