{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:25:52Z","timestamp":1759335952759},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T00:00:00Z","timestamp":1517875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 5\u2010year\u2010old indoor male neutered Siamese cat was presented with clinical signs of sneezing and chronic bilateral purulent nasal discharge. Multiple nasal cavity swabs were submitted for bacterial cultures, <jats:italic>Mycoplasma felis<\/jats:italic>\u2010<jats:styled-content style=\"fixed-case\">DNA qPCR<\/jats:styled-content>, and cytology. <jats:italic>M felis<\/jats:italic><jats:styled-content style=\"fixed-case\">qPCR<\/jats:styled-content> was positive and cytomorphologic diagnosis was severe, acute, purulent, rhinitis with intralesional protozoal microorganisms consistent with a <jats:italic>Trichomonas<\/jats:italic> spp. Nested <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">nPCR<\/jats:styled-content>) confirmed the diagnosis of <jats:italic>Tritrichomonas foetus<\/jats:italic>. Systemic therapy with doxycycline for <jats:italic>M felis<\/jats:italic> and metronidazole for <jats:italic>T foetus<\/jats:italic> was started with remission of clinical signs within 2 weeks; however, symptoms relapsed shortly after therapy was discontinued. This study represents the first documented case of <jats:italic>T foetus<\/jats:italic> associated with chronic nasal discharge in a cat, which supports the hypothesis that <jats:italic>T foetus<\/jats:italic> can live in the nasal cavity. It is also the first reported case of <jats:italic>M felis<\/jats:italic> and <jats:italic>T foetus<\/jats:italic> coinfection, which indicates that with mycoplasmal feline upper respiratory tract infections, <jats:italic>T foetus<\/jats:italic> should be considered as a coinfecting agent.<\/jats:p>","DOI":"10.1111\/vcp.12579","type":"journal-article","created":{"date-parts":[[2018,2,6]],"date-time":"2018-02-06T15:48:47Z","timestamp":1517932127000},"page":"294-296","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<i>Tritrichomonas foetus<\/i> and <i>Mycoplasma felis<\/i> coinfection in the upper respiratory tract of a cat with chronic purulent nasal discharge"],"prefix":"10.1111","volume":"47","author":[{"given":"Luca","family":"Pazzini","sequence":"first","affiliation":[{"name":"Veterinary Clinic Centro Storico\/Altstadt Bolzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Mugnaini","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Mancianti","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences University of Pisa Pisa Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"Ressel","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Science University of Liverpool Neston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,6]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1998.00702.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.40.11.4126-4130.2002"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00299-001-0399-7"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks1195"},{"key":"e_1_2_4_6_1","first-page":"1143","article-title":"Comparative analysis of Tritrichomonas foetus (Riedm\u00fcller, 1928) cat genotype, T. foetus (Riedm\u00fcller, cattle genotype and Tritrichomonas suis (Davaine, 1875) at 10 DNA loci","volume":"2012","author":"\u0160lapeta J","year":"1928","journal-title":"Inter J Parasitol"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.42-6-797"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.6.2707-2710.2004"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-10-13"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2007.00405.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.2307\/3274541"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2010.12.022"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X13489231"},{"key":"e_1_2_4_14_1","article-title":"Efficacy of guar gum\u2010based ronidazole capsules as a treatment for Tritrichomonas foetus infection in cats","volume":"10","author":"Grellet A","year":"2015","journal-title":"J Feline Med Surg"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2015.08.012"}],"container-title":["Veterinary Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvcp.12579","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vcp.12579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:54:31Z","timestamp":1695516871000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vcp.12579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,6]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/vcp.12579"],"URL":"https:\/\/doi.org\/10.1111\/vcp.12579","archive":["Portico"],"relation":{},"ISSN":["0275-6382","1939-165X"],"issn-type":[{"value":"0275-6382","type":"print"},{"value":"1939-165X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,6]]},"assertion":[{"value":"2018-02-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}