{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T19:18:07Z","timestamp":1758395887614},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T00:00:00Z","timestamp":1518048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 15\u2010year\u2010old spayed female domestic short\u2010haired cat with cutaneous\/subcutaneous well\u2010circumscribed, alopecic mass approximately 25\u00a0\u00d7\u00a030\u00a0mm in diameter, localized to the left shoulder region was brought to the veterinary surgery department. Despite the suggestive location and macroscopic appearance, feline injection\u2010site sarcoma was not suspected based on the cytologic examination of fine\u2010needle aspirates. The tumor was surgically resected, and tissue sections were evaluated microscopically. The tumor was found to be nonencapsulated with a distinct border between the neoplastic parenchyma and surrounding connective tissue. The neoplastic tissue consisted of 2 cell populations: elongated to spindle\u2010shaped cells arranged in bands and cords and malignant epithelial\u2010like cells. Both populations showed microscopic features of malignancy. Multinucleate giant cells with irregular cytoplasm were scattered among the neoplastic cells. The spindle\u2010shaped cells strongly expressed vimentin but did not express \u03b1\u2010smooth muscle actin (\u03b1\u2010<jats:styled-content style=\"fixed-case\">SMA<\/jats:styled-content>) or cytokeratin. Desmin was strongly expressed in about 0\u20105% of cells. Epithelial\u2010like cells expressed cytokeratin, but not vimentin, desmin, or \u03b1\u2010<jats:styled-content style=\"fixed-case\">SMA<\/jats:styled-content>. Multinucleate giant cells expressed vimentin, but did not \u03b1\u2010<jats:styled-content style=\"fixed-case\">SMA<\/jats:styled-content>, desmin, or cytokeratin. Based on microscopic observations and <jats:styled-content style=\"fixed-case\">IHC<\/jats:styled-content> results, the final diagnosis was carcinosarcoma with histologic features compatible with feline injection\u2010site sarcoma, but without the clinical aggressiveness of this tumor.<\/jats:p>","DOI":"10.1111\/vcp.12591","type":"journal-article","created":{"date-parts":[[2018,2,8]],"date-time":"2018-02-08T21:12:46Z","timestamp":1518124366000},"page":"297-302","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Carcinosarcoma mimicking a feline injection\u2010site sarcoma in a cat"],"prefix":"10.1111","volume":"47","author":[{"given":"Rafa\u0142","family":"Sapierzy\u0144ski","sequence":"first","affiliation":[{"name":"Department of Pathology and Veterinary Diagnostics Faculty of Veterinary Medicine Warsaw University of Life Sciences (SGGW) Warsaw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,2,8]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870301500213"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.157.12.356"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2012.01.022"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1040638713495389"},{"key":"e_1_2_3_6_1","first-page":"430","article-title":"Feline postvaccinal sarcoma: 20\u00a0years later","volume":"53","author":"Wilcock B","year":"2012","journal-title":"Can Vet J"},{"key":"e_1_2_3_7_1","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1515\/pjvs-2015-0041","article-title":"Epidemiological and morphological analysis of feline injection site sarcomas","volume":"18","author":"Kliczkowska\u2010Klarowicz K","year":"2015","journal-title":"Pol J Vet Sci"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2010.04.025"},{"key":"e_1_2_3_9_1","article-title":"DNA damage is a feature of feline injection\u2010site sarcoma","author":"Kang S","year":"2016","journal-title":"Vet Comp Oncol"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1354\/vp.39-1-33"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12067"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X12472174"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-9-17"}],"container-title":["Veterinary Clinical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvcp.12591","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vcp.12591","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:54:33Z","timestamp":1695516873000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vcp.12591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,8]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1111\/vcp.12591"],"URL":"https:\/\/doi.org\/10.1111\/vcp.12591","archive":["Portico"],"relation":{},"ISSN":["0275-6382","1939-165X"],"issn-type":[{"value":"0275-6382","type":"print"},{"value":"1939-165X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,8]]},"assertion":[{"value":"2018-02-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}