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They are captured worldwide by commercial and recreational fisheries, but little is known about the effects that fishing has on the homeostasis and longevity of these animals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aimed to assess the health of Shortfin Mako sharks captured by recreational fishers off eastern Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010four sharks were captured, and their gender, length, weight, reproductive maturity, and stage were recorded. After blood and urine collection, serum analytes were quantified using standard biochemical methods, whereas urine was analyzed using semi\u2010quantitative reagent strips, microscopic examination, centrifugation, and ammonium sulfate precipitation tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six Makos presented with red\u2010brown urine. The means of notable serum analytes were as follows: sodium 276\u00a0mmol\/L, potassium 15.6\u00a0mmol\/L, inorganic phosphate 10.6\u00a0mmol\/L, magnesium 3.3\u00a0mmol\/L, urea 325\u00a0mmol\/L, creatinine 52\u00a0\u03bcmol\/L, AST 2806 U\/L, CK 240938 U\/L, lactate 44.4\u00a0mmol\/L, osmolarity 1160\u00a0mmol\/L, and pH 7.13. These analytes differed from the respective sand tiger shark reference interval, which was used as a proxy for Makos. The red\u2010brown urine was due to myoglobin and had a mean pH of 5.76 that, when combined with red\u2010brown casts, led to a diagnosis of fishing\u2010induced exertional rhabdomyolysis that occurred secondary to lactic acidosis, hypoxia, and hypovolemia. It was further exacerbated by hyperkalemia and acute renal failure, serious complications that often lead to mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Practitioners caring for sharks and rays should consider collecting urine from free\u2010living or aquarium animals when they are captured for examination and\/or treatment, particularly at times with maximal seawater temperatures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vcp.12824","type":"journal-article","created":{"date-parts":[[2020,2,24]],"date-time":"2020-02-24T03:20:18Z","timestamp":1582514418000},"page":"23-41","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Capture\u2010induced exertional rhabdomyolysis in the Shortfin Mako Shark, <i>Isurus oxyrinchus<\/i>"],"prefix":"10.1111","volume":"49","author":[{"given":"Nicholas M.","family":"Otway","sequence":"first","affiliation":[{"name":"New South Wales Department of Primary Industries Port Stephens Fisheries Institute Taylors Beach NSW Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,23]]},"reference":[{"key":"e_1_2_7_2_1","volume-title":"Sharks and Rays of Australia","author":"Last PR","year":"2009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10082"},{"key":"e_1_2_7_4_1","volume-title":"Using Satellite Tagging and Molecular Techniques to Improve the Ecologically Sustainable Fisheries Management of Shortfin Makos (Isurus oxyrinchus) in the Australasian Region","author":"Rogers PJ","year":"2015"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3354\/meps11646"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1139\/f82-058"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1071\/MF9840573"},{"key":"e_1_2_7_8_1","first-page":"489","article-title":"Length at maturity in three pelagic sharks (Lamna nasus, Isurus oxyrinchus, and Prionace glauca) from New Zealand","volume":"103","author":"Francis MP","year":"2005","journal-title":"Fish Bull"},{"key":"e_1_2_7_9_1","first-page":"299","article-title":"Reproductive biology of the female shortfin mako, Isurus oxyrinchus Rafinesque, 1810, with comments on the embryonic development of lamnoids","volume":"98","author":"Mollet HF","year":"2000","journal-title":"Fish Bull"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.2307\/1444706"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1071\/MF05077"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10641-006-9127-z"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-406X(69)91335-8"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1086\/physzool.54.3.30159948"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00695777"},{"key":"e_1_2_7_16_1","first-page":"92","article-title":"Temperature, heat production and heat exchange in Lamnid sharks","volume":"9","author":"Carey FG","year":"1985","journal-title":"Mem Southern Calif Acad Sci"},{"key":"e_1_2_7_17_1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1242\/jeb.151.1.175","article-title":"Aspects of shark swimming performance determined using a large water tunnel","volume":"151","author":"Graham JB","year":"1990","journal-title":"J Exp Biol"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.10845"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.00481"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00227-007-0757-2"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.060095"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00345662"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.00504"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10695-015-0055-8"},{"key":"e_1_2_7_25_1","first-page":"341","volume-title":"Overview of World Elasmobranch Fisheries","author":"Bonfil R","year":"1994"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1071\/MF00086"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1051\/alr\/2009044"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1071\/MF9920213"},{"key":"e_1_2_7_29_1","volume-title":"The NSW Game Fish Tournament Monitoring Program 1994\u20132013: Data summary and assessment of program role and design","author":"Ghosn DL","year":"2015"},{"key":"e_1_2_7_30_1","unstructured":"CaillietGM CavanaghRD KulkaDW et al.Isurus oxyrinchus. 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