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Examination of a buffy coat preparation and splenic and liver aspirates revealed a monomorphic population of plasmacytoid cells, and the same cells comprised approximately 90% of bone marrow samples submitted for cytologic and histologic evaluation. Biochemistry revealed a hypoglobulinemia, and the presence of an M\u2010protein was not supported by serum and urine protein electrophoresis or serum immunofixation. Immunohistochemistry demonstrated strong nuclear labeling for MUM\u20101.<\/jats:p>","DOI":"10.1111\/vcp.12948","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T07:49:09Z","timestamp":1619682549000},"page":"227-235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Hypoglobulinemia in a dog with disseminated plasma cell neoplasia: Case report and review of the diagnostic criteria"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0203-7731","authenticated-orcid":false,"given":"Juliet E.","family":"Brown","sequence":"first","affiliation":[{"name":"U\u2010Vet Werribee Animal Hospital and Faculty of Veterinary and Agricultural Science University of Melbourne Werribee Vic. 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