{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T10:14:15Z","timestamp":1788948855005,"version":"build-2803163510"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,10,24]],"date-time":"2021-10-24T00:00:00Z","timestamp":1635033600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000853","name":"University of Glasgow","doi-asserted-by":"publisher","award":["200090\u201001"],"award-info":[{"award-number":["200090\u201001"]}],"id":[{"id":"10.13039\/501100000853","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Canine lymphoma represents a heterogeneous group of lymphoid neoplasms, with multicentric nodal lymphoma being the most common presentation. Musculoskeletal involvement is uncommon, and primary muscular lymphoma is a very rare presentation. Only a few cases have been described in dogs, which were of variable classification and immunophenotype. Here, we report the case of a 5\u2010year\u2010old female neutered Beagle that presented with an intramuscular mass on the right shoulder and associated lameness and lethargy. One month after initial presentation, multiple cutaneous nodules appeared on the head, and staging with advanced imaging revealed additional masses affecting other muscles. Cytology, histopathology, immunohistochemistry, and PCR for antigen receptor rearrangements of one of the muscle masses and skin lesions supported a diagnosis of peripheral T\u2010cell lymphoma with large granular lymphocytes at both sites. The dog was euthanized after diagnosis due to the poor prognosis. This is the first report of primary muscular peripheral T\u2010cell lymphoma with large granular lymphocytes and cutaneous involvement in the dog. Despite being a rare presentation, lymphoma must be considered a differential in dogs presenting with a discrete, intramuscular, soft tissue mass.<\/jats:p>","DOI":"10.1111\/vcp.13021","type":"journal-article","created":{"date-parts":[[2021,10,25]],"date-time":"2021-10-25T04:18:51Z","timestamp":1635135531000},"page":"584-588","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Primary multifocal muscular T\u2010cell lymphoma with cutaneous involvement in a dog: A case report and review of the literature"],"prefix":"10.1111","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9863-1684","authenticated-orcid":false,"given":"Mariana G.","family":"Lopes","sequence":"first","affiliation":[{"name":"School of Veterinary Medicine Small Animal Hospital College of Medical, Veterinary, and Life Sciences University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1179-5788","authenticated-orcid":false,"given":"Francesco","family":"Marchesi","sequence":"additional","affiliation":[{"name":"Veterinary Diagnostic Services School of Veterinary Medicine University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6738-0189","authenticated-orcid":false,"given":"Hayley","family":"Haining","sequence":"additional","affiliation":[{"name":"Veterinary Diagnostic Services School of Veterinary Medicine University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5975-2475","authenticated-orcid":false,"given":"Joanna S.","family":"Morris","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine Small Animal Hospital College of Medical, Veterinary, and Life Sciences University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,10,24]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2009.0391.x"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-36-1-63"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.09-0454"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063870802000621"},{"issue":"524","key":"e_1_2_4_6_1","first-page":"17","article-title":"Epitheliotropic T\u2010cell gastrointestinal tract lymphosarcoma with metastases to lung and skeletal muscle in a cat","volume":"216","author":"Krecic MR","year":"2000","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12015"},{"key":"e_1_2_4_8_1","volume-title":"Tumors in Domestic Animals","author":"Valli 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