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The patient's seizures were well controlled with a combination of anticonvulsants. During a manual blood smear review at a follow\u2010up appointment, double Barr bodies were identified in segmented neutrophils. Karyotyping revealed that the patient is mosaic for X\u2010monosomy and X\u2010trisomy, a finding that has never been reported in a dog and is rarely reported in people. This case demonstrates how the identification of abnormal neutrophil nuclear appendages may correlate with chromosomal abnormalities in dogs.<\/jats:p>","DOI":"10.1111\/vcp.13261","type":"journal-article","created":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T05:12:26Z","timestamp":1689311546000},"page":"583-587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A rare finding of double Barr bodies and <scp>X\u2010monosomy<\/scp>\/<scp>X\u2010trisomy<\/scp> mosaicism in a dog with presumed idiopathic epilepsy"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7916-4387","authenticated-orcid":false,"given":"Nicholas T.","family":"Noto","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Medicine University of Illinois College of Veterinary Medicine  Urbana Illinois 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