{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T18:23:53Z","timestamp":1780079033399,"version":"3.54.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Clinical Pathol"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 6\u2010year\u2010old 21.5\u2009kg castrated male Siberian Husky was presented for acute onset of lethargy, vomiting, hemorrhagic diarrhea, and inappetence. Physical examination revealed marked discomfort upon abdominal palpation and 5%\u20137% dehydration. The CBC and biochemical profile revealed changes consistent with mild to moderate inflammation, dehydration, and gastrointestinal (GI) disease. Despite aggressive gastrointestinal support, anorexia persisted, and an upper GI endoscopy was performed in conjunction with esophagostomy tube placement. Endoscopy revealed abnormal gastric mucosa characterized by moderately well\u2010demarcated areas of blue\u2010black discoloration. Impression smears of a gastric biopsy revealed abundant extracellular yeasts with morphology most consistent with <jats:italic>Candida<\/jats:italic> spp. and frequent extracellular cocci. Similar yeast and bacteria, in lower numbers, were observed on cytologic analysis of a direct smear of the rectal mucosa. A rectal swab submitted for fungal culture yielded pure growth of fungal yeasts identified as <jats:italic>Diutina<\/jats:italic> (formerly <jats:italic>Candida<\/jats:italic>) <jats:italic>rugosa<\/jats:italic> by matrix\u2010assisted laser desorption\u2010ionization time\u2010of\u2010flight mass spectrometry. The dog's clinical signs improved with fluconazole, and he was discharged. Follow\u2010up fungal culture of a rectal swab showed no growth of <jats:italic>D. rugosa<\/jats:italic>. To the authors' knowledge, this is the first case report that describes the clinical, hematologic, cytologic, and gross findings of enteric colonization by <jats:italic>D. rugosa<\/jats:italic> in a dog.<\/jats:p>","DOI":"10.1111\/vcp.13335","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T03:11:17Z","timestamp":1709176277000},"page":"255-260","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Gastrointestinal colonization by <i>Diutina (Candida) rugosa<\/i> in a 6\u2010year\u2010old Siberian Husky"],"prefix":"10.1111","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2380-9374","authenticated-orcid":false,"given":"Nina K.","family":"Randolph","sequence":"first","affiliation":[{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine The Ohio State University  Columbus Ohio 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