{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:05:42Z","timestamp":1762430742986},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T00:00:00Z","timestamp":1370390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2013,8]]},"abstract":"Background<\/jats:title>In humans, rapidly developing P<\/jats:styled-content>asteurella multocida<\/jats:italic> cellulitis after a cat scratch or bite is a well\u2010known entity that sometimes progresses to necrotizing fasciitis and can be fatal.<\/jats:p><\/jats:sec>Case report<\/jats:title>A 3\u2010year\u2010old female spayed whippet dog developed ecchymosis, swelling and pain within 24\u00a0h of being scratched by a cat on the ventral thorax. Over the following days, while being treated only with pain medications, the lesions rapidly progressed into haemorrhagic bullae with expanding skin necrosis. A heavy growth of P<\/jats:styled-content>.\u00a0multocida<\/jats:italic> was seen on bacterial cultures, and histological examination showed marked, suppurative panniculitis with necrosis of the epidermis, dermis and panniculus. Special histological stains highlighted a moderate amount of Gram\u2010negative coccobacilli admixed with inflammatory cells. Complete resolution was achieved with surgical debridement, skin grafting and intravenous antibiotic treatment. Positive bacterial culture for P<\/jats:styled-content>.\u00a0multocida<\/jats:italic>, in conjunction with the history, clinical findings, histology results and the rapid response to therapy, strongly supports a diagnosis of P<\/jats:styled-content>.\u00a0multocida<\/jats:italic> necrotizing cellulitis.<\/jats:p><\/jats:sec>Conclusions and clinical importance<\/jats:title>Complications of cat bite\u2010associated P<\/jats:styled-content>.\u00a0multocida<\/jats:italic> infections in humans are well known. To the authors' knowledge, this is the first documentation of P<\/jats:styled-content>.\u00a0multocida<\/jats:italic> necrotizing cellulitis in a dog following a cat scratch wound. This case highlights the rapidity and severity of P<\/jats:styled-content>.\u00a0multocida<\/jats:italic> cellulitis, if not recognized and treated early. Veterinarians should include P<\/jats:styled-content>.\u00a0multocida<\/jats:italic> in the differential diagnosis of any local wound infection following a cat scratch.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12038","type":"journal-article","created":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T12:05:03Z","timestamp":1370433903000},"page":"463","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Cat scratch\u2010induced P<\/scp>asteurella multocida<\/i> necrotizing cellulitis in a dog"],"prefix":"10.1111","volume":"24","author":[{"given":"Frane","family":"Banovic","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences NC State University College of Veterinary Medicine 1052 William Moore Drive Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith","family":"Linder","sequence":"additional","affiliation":[{"name":"Department of Population Health and Pathobiology NC State University College of Veterinary Medicine 1052 William Moore Drive Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Boone","sequence":"additional","affiliation":[{"name":"Department of Population Health and Pathobiology NC State University College of Veterinary Medicine 1052 William Moore Drive Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Jennings","sequence":"additional","affiliation":[{"name":"Department of Population Health and Pathobiology NC State University College of Veterinary Medicine 1052 William Moore Drive Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. Marcia","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences NC State University College of Veterinary Medicine 1052 William Moore Drive Raleigh NC 27607 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,5]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198405000-00001"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/14.3.633"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246665"},{"key":"e_1_2_4_5_1","first-page":"1804","article-title":"Cellulitis and erysipelas","volume":"9","author":"Morris A","year":"2003","journal-title":"Clin Evid"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198105000-00006"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365540600786572"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1179\/acb.2010.65.6.007"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.2217\/fmb.10.91"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1863-2378.2008.01152.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2011.032"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200308000-00005"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198406283102601"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10156-004-0331-5"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02447933"},{"key":"e_1_2_4_16_1","first-page":"464","volume-title":"Canine and Feline Endocrinology and Reproduction","author":"Feldman EC","year":"2004"},{"key":"e_1_2_4_17_1","first-page":"328","volume-title":"Infectious Diseases of the Dog and Cat","author":"Greene C","year":"1998"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM195910292611803"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvde.12038","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12038","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T09:13:23Z","timestamp":1696151603000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6,5]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1111\/vde.12038"],"URL":"https:\/\/doi.org\/10.1111\/vde.12038","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6,5]]},"assertion":[{"value":"2013-04-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-06-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}