{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T17:54:04Z","timestamp":1791395644872,"version":"4.3.3"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,5]],"date-time":"2014-03-05T00:00:00Z","timestamp":1393977600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Atopic dermatitis (<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>) is recognized as a common cause of pruritus in cats, but it remains incompletely characterized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis\/Objectives<\/jats:title><jats:p>The aim of the study was to evaluate cases of confirmed feline <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Fourty\u2010five cats from a dermatology referral practice (2001\u20132012).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective case record review was carried out using strict diagnostic criteria, including exclusion of flea\u2010bite hypersensitivity and adverse food reaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Disease prevalence was 12.5%, with domestic mixed (<jats:italic>n<\/jats:italic>\u00a0=\u00a024), Abyssinian (<jats:italic>n<\/jats:italic>\u00a0=\u00a06) and Devon rex (<jats:italic>n<\/jats:italic>\u00a0=\u00a03) cat breeds predisposed. Median age of onset was 2\u00a0years (62% &lt;3\u00a0years; 22% &gt;7\u00a0years; range 3\u00a0months to 12\u00a0years). Common presentations were severe (82%), nonseasonal (82%), waxing\/waning (36%) pruritus, with alopecia\/crusting\/excoriations and\/or erosions\/ulceration (73%). Miliary dermatitis (20%) and eosinophilic granuloma complex lesions (27%) occurred. The face\/head (71%), ventral abdomen (51%), neck (51%), limbs (38%), pinnae (31%), dorsum\/rump (31%) and feet (16%) were frequently affected sites; lesions were restricted to the head\/neck in only five cats (11%). Concurrent otitis externa (16%), superficial bacterial pyoderma (49%), <jats:italic>Malassezia<\/jats:italic> dermatitis (7%), flea\u2010bite hypersensitivity (24%) and adverse food reaction (13%) occurred. Strong reactions on intradermal allergen testing were common (68%; 19 of 30), most frequently to pollens (61%) and\/or insects (46%). Good response to ciclosporin (100%; 10 of 10), systemic glucocorticoids (55%; 22 of 40) and allergen\u2010specific immunotherapy (57%; 13 of 23) and good\/partial response to antihistamines (67%; 22 of 33) were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>The prevalence of feline <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> was higher than previously suggested, and breed predispositions were confirmed. Severe nonseasonal pruritus was most common, with a varied spectrum of lesions affecting a range of body areas.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12109","type":"journal-article","created":{"date-parts":[[2014,3,5]],"date-time":"2014-03-05T13:01:18Z","timestamp":1394024478000},"page":"95","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Feline atopic dermatitis: a retrospective study of 45 cases (2001\u20132012)"],"prefix":"10.1111","volume":"25","author":[{"given":"Philippa A.","family":"Ravens","sequence":"first","affiliation":[{"name":"Small Animal Specialist Hospital Level 1, 1 Richardson Place North Ryde NSW 2113 Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei J.","family":"Xu","sequence":"additional","affiliation":[{"name":"University of Sydney Veterinary Teaching Hospital 410 Werombi Road Brownlow Hill NSW 2570 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