{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T16:42:59Z","timestamp":1783183379151,"version":"3.54.6"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T00:00:00Z","timestamp":1399248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Perianal pruritus has been reported in dogs with anal sac disease but not in healthy dogs. Some authors describe it as typical of allergy, but there is little evidence in support of this.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis\/Objectives<\/jats:title><jats:p>The aim was to investigate the association between perianal pruritus and canine atopic dermatitis (<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>), adverse food reaction (<jats:styled-content style=\"fixed-case\">ARF<\/jats:styled-content>) and other skin diseases in dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Two hundred and fifty privately owned dogs with skin disease and without anal sac disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The presence or absence of perianal pruritus, macroscopic and cytological evaluation of the perianal skin surface and the macroscopic appearance of anal sac contents were assessed. Chi\u2010square and Fisher's exact tests were performed to compare the frequency of perianal pruritus with the clinical diagnoses and with clinical and cytological parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Perianal pruritus was seen in 39 of 75 dogs with<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>, in 29 of 57 dogs with<jats:styled-content style=\"fixed-case\">ARF<\/jats:styled-content>and in only 24 of 118 dogs with other conditions. The frequency of perianal pruritus in dogs with<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>and\/or<jats:styled-content style=\"fixed-case\">ARF<\/jats:styled-content>was significantly higher than that in dogs with other diagnoses (<jats:italic>P\u00a0&lt;\u00a0<\/jats:italic>0.0001). No other disease was significantly associated with perianal pruritus. Perianal pruritus was significantly associated with signs of perianal alopecia, erythema, excoriations, lichenification and hyperpigmentation; it was not associated with the presence of bacteria or yeasts or with anal sac impaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>Perianal pruritus was seen more frequently in dogs with<jats:styled-content style=\"fixed-case\">AFR<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">CAD<\/jats:styled-content>than with other dermatological diseases. This is the first study to evaluate perianal pruritus in dogs with skin disease and without anal sac disease.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12127","type":"journal-article","created":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T05:37:05Z","timestamp":1399268225000},"page":"204","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Perianal pruritus in dogs with skin disease"],"prefix":"10.1111","volume":"25","author":[{"given":"Elisa","family":"Maina","sequence":"first","affiliation":[{"name":"Servizi Dermatologici Veterinari Strada Bedale della Ressia 2 12016 Peveragno Cuneo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Galzerano","sequence":"additional","affiliation":[{"name":"Private practitioner Via Macchieraldo 19 13900 Biella BI Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Noli","sequence":"additional","affiliation":[{"name":"Private practitioner Via Macchieraldo 19 13900 Biella BI Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,5,5]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1308\/003588408X317940"},{"key":"e_1_2_6_3_1","first-page":"511","article-title":"Pruritus ani","volume":"33","author":"Heard S","year":"2004","journal-title":"Aust Fam Physician"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2009.09.007"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31818080c0"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2005.00031.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2010.00916.x"},{"key":"e_1_2_6_8_1","first-page":"436","volume-title":"Strombeck's Small Animal Gastroenterology","author":"Guilford WG","year":"1996"},{"key":"e_1_2_6_9_1","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2460\/javma.1993.203.02.259","article-title":"Diagnosis of food allergy in dogs","volume":"203","author":"Rosser EJ","year":"1993","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.154.17.519"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.1411"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2010.00951.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2012.01092.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2009.00758.x"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2008.00669.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3164.2002.00310.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2006.00522.x"},{"key":"e_1_2_6_18_1","first-page":"137","volume-title":"Parasitology for Veterinarians","author":"Georgi JR","year":"1990"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2006.08.013"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2003.tb11418.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.2004.00629.x"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvde.12127","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvde.12127","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12127","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,26]],"date-time":"2024-05-26T09:42:30Z","timestamp":1716716550000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,5]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1111\/vde.12127"],"URL":"https:\/\/doi.org\/10.1111\/vde.12127","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,5]]},"assertion":[{"value":"2014-02-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-05-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}