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Significant differences in the magnitude of IgE reactivity between groups for each allergen were seen only for lamb (Laboratory\u00a0A,<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.003); lamb reactivity in Group\u00a0D exceeded Group\u00a0E (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.004) but was comparable between all other groups. Agreement (kappa statistic) between the two laboratories\u2019 tests was \u2018moderate\u2019 for one antigen (potato IgE), \u2018fair\u2019 for four (corn IgE, rice IgE and IgG and soya bean IgG), \u2018slight\u2019 for eight (six IgE and two IgG) and \u2018less than chance\u2019 for the remaining six antigens (three IgE and three IgG).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>These laboratories\u2019 tests appear to have dubious predictive clinical utility because they neither correlate nor distinguish between dogs of different disease status.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12137","type":"journal-article","created":{"date-parts":[[2014,6,2]],"date-time":"2014-06-02T05:25:00Z","timestamp":1401686700000},"page":"447","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Food\u2010specific serum<scp>I<\/scp>g<scp>E<\/scp>and<scp>I<\/scp>g<scp>G<\/scp>reactivity in dogs with and without skin disease: lack of correlation between laboratories"],"prefix":"10.1111","volume":"25","author":[{"given":"Jonathan I.","family":"Hardy","sequence":"first","affiliation":[{"name":"Department of Clinical Science and Services and Royal Veterinary College Hawkshead Lane North Mymms Hatfield Hertfordshire AL9 7TA UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anke","family":"Hendricks","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services and Royal Veterinary College Hawkshead Lane North Mymms Hatfield Hertfordshire AL9 7TA UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"Loeffler","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services and Royal Veterinary College Hawkshead Lane North Mymms Hatfield Hertfordshire AL9 7TA UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Mei","family":"Chang","sequence":"additional","affiliation":[{"name":"Department of Research Office Royal Veterinary College Royal College Street London NW1 0TU UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristien L.","family":"Verheyen","sequence":"additional","affiliation":[{"name":"Department of Production and Population Health Royal Veterinary College Hawkshead Lane North Mymms Hatfield Hertfordshire AL9 7TA UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver A.","family":"Garden","sequence":"additional","affiliation":[{"name":"Department of Regulatory T Cell Laboratory Royal Veterinary College Royal College Street London NW1 0TU UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross","family":"Bond","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services and Royal Veterinary College Hawkshead Lane North 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