{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T08:40:01Z","timestamp":1766047201848},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T00:00:00Z","timestamp":1459123200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Society of Cynologic Research"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Cheilitis is a common presentation in dogs associated with a variety of skin diseases and often complicated by microbial infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe and compare clinical and cytological features and bacterial culture results from the lower lips of dogs with cheilitis (as compared to healthy controls), and to evaluate three cytology sampling techniques for their abilities to differentiate between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Fifty six dogs with cheilitis and 54 controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Anatomy and clinical signs of the lower lip were recorded. Cytology samples taken by tape strip, direct impression and swabs rolled over skin were scored semiquantitatively for microorganisms, inflammatory cells and keratinocytes. Cytology scores were correlated with semiquantitative bacterial culture scores.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Pure breeds, frequency of lip folds and all cytology scores except keratinocytes were higher in dogs with cheilitis than in controls, but a substantial overlap was seen in all microorganisms between the groups. Hypersensitivity disorders were diagnosed in 40 of 56 dogs with cheilitis. The tape strip technique yielded the greatest differences between groups. Bacterial growth was reported in 100% of dogs with cheilitis and in 93% of the controls. Pathogens such as<jats:italic>Staphylococcus pseudintermedius, Escherichia coli<\/jats:italic>and<jats:italic>Pseudomonas<\/jats:italic>spp were found more frequently in dogs with cheilitis. Cytology and bacterial culture were poorly correlated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cheilitis was associated with primary hypersensitivity disorders and the presence of a lip fold was a predisposing factor. Results of aerobic culture were similar to prior studies on pyoderma of other body sites, except for higher rates of<jats:italic>Pseudomonas<\/jats:italic>spp. isolation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12300","type":"journal-article","created":{"date-parts":[[2016,3,28]],"date-time":"2016-03-28T10:38:25Z","timestamp":1459161505000},"page":"140","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinical features, cytology and bacterial culture results in dogs with and without cheilitis and comparison of three sampling techniques"],"prefix":"10.1111","volume":"27","author":[{"given":"Maren","family":"Doelle","sequence":"first","affiliation":[{"name":"Tieraerztliche Spezialisten Rodigallee 85 D\u201022043 Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anette","family":"Loeffler","sequence":"additional","affiliation":[{"name":"Department of Clinical Science and Services Royal Veterinary College Hawkshead Lane North Mymms Hertfordshire AL9 7TA UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Wolf","sequence":"additional","affiliation":[{"name":"Institute of Veterinary Physiology Department of Veterinary Medicine Freie Universit\u00e4t Berlin Oertzenweg 19b D\u201014163 Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veit","family":"Kostka","sequence":"additional","affiliation":[{"name":"synlab.vet GmbH Labor Hamburg Schillerstr. 29 D\u201021502 Geesthacht Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Linek","sequence":"additional","affiliation":[{"name":"Tieraerztliche Spezialisten Rodigallee 85 D\u201022043 Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2016,3,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.32602"},{"key":"e_1_2_6_3_1","first-page":"293","volume-title":"Klinische Anatomie der Kopf\u2010 und Halsregion f\u00fcr Zahnmediziner","author":"Rosenbauer KA","year":"1998"},{"key":"e_1_2_6_4_1","first-page":"75","volume-title":"Atlas der Anatomie des Menschen","author":"Tillmann B","year":"2005"},{"key":"e_1_2_6_5_1","first-page":"489","volume-title":"Dermatology","author":"Sterry W","year":"2006"},{"key":"e_1_2_6_6_1","first-page":"846","volume-title":"Fitzpatrick's Dermatology in General Medicine","author":"Woo SB","year":"2012"},{"key":"e_1_2_6_7_1","first-page":"281","volume-title":"Miller's Anatomy of the Dog","author":"Miller ME","year":"2012"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12202"},{"key":"e_1_2_6_9_1","first-page":"588","volume-title":"Muller and Kirk's Small Animal Dermatology","author":"Miller WH","year":"2013"},{"key":"e_1_2_6_10_1","first-page":"352","volume-title":"Textbook of Small Animal Surgery","author":"White R","year":"2003"},{"key":"e_1_2_6_11_1","first-page":"372","volume-title":"Muller and Kirk's Small Animal Dermatology","author":"Miller WH","year":"2013"},{"key":"e_1_2_6_12_1","first-page":"347","volume-title":"Muller and Kirk's Small Animal Dermatology","author":"Miller WH","year":"2013"},{"key":"e_1_2_6_13_1","first-page":"618","volume-title":"Kirk's Current Veterinary Therapy. 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