{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T17:58:35Z","timestamp":1789322315869,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T00:00:00Z","timestamp":1478563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Lynxacarus radovskyi<\/jats:italic> has been observed in cats in Malaysia; previously treatment with fipronil and moxidectin\/imidacloprid spot\u2010on has been described.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To compare the efficacy of two spot\u2010on treatments of moxidectin\/imidacloprid, two\u00a0weeks apart to a single oral dose of fluralaner against <jats:italic>Lynxacarus radovskyi<\/jats:italic> and evaluate time to re\u2010infestation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty cats were assigned to three groups of ten cats each. Group 1 received one 250\u00a0mg fluralaner tablet. Group 2 received two doses of moxidectin\/imidacloprid spot\u2010on two\u00a0weeks apart. Group 3 consisted of untreated controls. For each cat, three plucks of about 50 hairs each were collected from three sites (dorsal neck, lateral thigh and perineal\/tail region) for a total of nine pluckings every two\u00a0weeks. Severity of infestation was scored from 0 (no parasite), to 1 (only nonhatched eggs), 2 (both hatched and nonhatched eggs), 3 (&lt;50 mites) and 4 (&gt;50 mites). Efficacy was compared between treatment groups and over time in the same group, and results analysed statistically. Re\u2010infestation was defined as the identification of new eggs or mites on hair pluckings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Moxidectin\/imidacloprid spot\u2010on and oral fluralaner achieved 100% eradication within 28\u00a0days. No significant difference was observed between groups 1 and 2; re\u2010infestation occurred by Day 56 in both treatment groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A single dose of oral fluralaner or two moxidectin\/imidacloprid spot\u2010on treatments two\u00a0weeks apart are efficacious in the eradication of <jats:italic>L.\u00a0radovskyi<\/jats:italic> in cats and able to prevent re\u2010infestation for at least 42\u00a0days post\u2010treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12390","type":"journal-article","created":{"date-parts":[[2016,11,9]],"date-time":"2016-11-09T20:17:21Z","timestamp":1478722641000},"page":"474","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Efficacy and duration of action of oral fluralaner and spot\u2010on moxidectin\/imidacloprid in cats infested with <i>Lynxacarus radovskyi<\/i>"],"prefix":"10.1111","volume":"27","author":[{"given":"Hock Siew","family":"Han","sequence":"first","affiliation":[{"name":"Han Veterinary Surgery 50 JLN Molek 2\/2, TMN Molek 81100 Johor Bahru Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Noli","sequence":"additional","affiliation":[{"name":"Servizi Dermatologici Veterinari Strada Bedale della Ressia 2 12016 Peveragno (CN) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Cena","sequence":"additional","affiliation":[{"name":"Department of Translational Medicine Unit of Medical Statistics and Cancer Epidemiology University \u201cAmedeo Avogadro\u201d of Piemonte Orientale Via Solaroli 17 Novara Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,8]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmedent\/11.2.211"},{"key":"e_1_2_5_3_1","first-page":"308","article-title":"The cat fur mite, Lynxacarus radovskyi Tenorio, 1974 (Acarina: Astigmata: Listrophoridae) from cat, Felis catus in Peninsular Malaysia","volume":"29","author":"Jeffery J","year":"2012","journal-title":"Trop Biomed"},{"key":"e_1_2_5_4_1","first-page":"105","article-title":"Occurrence of Lynxacarus radovskyi (Tenario,1974) in cats in Batong Malate, Los Banos, Laguna","volume":"41","author":"Moya GC","year":"2004","journal-title":"Philip J Vet Med"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1978.tb02521.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1979.tb15178.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.2000.36167"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12177"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2004.00414_30.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-7-87"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-016-1564-8"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12353"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2012.01075.x"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvde.12390","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,2]],"date-time":"2023-10-02T02:23:21Z","timestamp":1696213401000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,8]]},"references-count":12,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["10.1111\/vde.12390"],"URL":"https:\/\/doi.org\/10.1111\/vde.12390","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,8]]},"assertion":[{"value":"2016-08-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}