{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T23:13:38Z","timestamp":1782861218652,"version":"3.54.5"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T00:00:00Z","timestamp":1480896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Infestation of wounds with the larvae of Callophorid flies is relatively common in countries where these parasites are found. The most common species associated with infections in Southeast Asia is <jats:italic>Chrysomya bezziana<\/jats:italic> (<jats:italic>Ch. bezziana<\/jats:italic>), the Old World screw worm. Treatment consists of either subcutaneous injection of ivermectin or oral administration of nitenpyram combined with aggressive tissue debridement under general anaesthesia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the treatment of cutaneous myiasis in three dogs caused by the larvae of <jats:italic>Ch. bezzian<\/jats:italic>a in Malaysia and their treatment with spinosad plus milbemycin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In all dogs, a single oral dose of spinosad plus milbemycin at the recommended dosage of 31\u201362 mg\/kg and 0.5\u20131.0 mg\/kg, respectively, was able to kill all larvae within 8 h. Most dead larvae fell off the host and those remaining on the host were dead and easily removed with simple saline flushing and gentle debridement. Neither general anaesthesia nor aggressive mechanical debridement were needed in any patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>Oral spinosad plus milbemycin is a safe, licensed and effective treatment at the recommended dose for the rapid elimination of <jats:italic>Ch. bezziana<\/jats:italic> myiasis, with no need for sedation or anaesthesia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12403","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T10:19:32Z","timestamp":1480933172000},"page":"239","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["<i>Chrysomya bezziana<\/i> (Diptera: Calliphoridae) infestation: case report of three dogs in Malaysia treated with spinosad\/milbemycin"],"prefix":"10.1111","volume":"28","author":[{"given":"Hock Siew","family":"Han","sequence":"first","affiliation":[{"name":"Han Veterinary Surgery 50 JLN Molek 2\/2 TMN Molek 81100 Johor Bahru Johor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reuben","family":"Sharma","sequence":"additional","affiliation":[{"name":"Veterinary Laboratory Unit Faculty of Veterinary Medicine Unversity Putra Malaysia 43400 Serdang Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Jeffery","sequence":"additional","affiliation":[{"name":"Veterinary Laboratory Unit Faculty of Veterinary Medicine Unversity Putra Malaysia 43400 Serdang Selangor Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Noli","sequence":"additional","affiliation":[{"name":"Servizi Dermatologici Veterinari Strada Bedale della Ressia 2 12016 Peveragno (CN) Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,5]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470690505"},{"key":"e_1_2_4_3_1","first-page":"296","volume-title":"Veterinary Clinical Parasitology","author":"Greiner E","year":"2014"},{"key":"e_1_2_4_4_1","first-page":"26","volume-title":"Georgis\u2019 Parasitology for Veterinarians","author":"Bowman DD","year":"2014"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2004.tb12677.x"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.127626"},{"key":"e_1_2_4_7_1","first-page":"454","article-title":"A case of oral myiasis due to Chrysomnya bezziana","volume":"9","author":"Ng KHL","year":"2003","journal-title":"Hong Kong Med 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