{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:43:14Z","timestamp":1761896594432,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,7,23]],"date-time":"2017-07-23T00:00:00Z","timestamp":1500768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Mycetoma is a chronic, proliferative lesion of cutaneous\/subcutaneous tissue characterized by draining tracts and granules in the discharge caused by actinomycetes (actinomycetoma) or filamentous fungi (eumycotic mycetoma).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This case report describes the unusual finding of a cutaneous mycetoma of the lateral wing of the right nostril in a gelding.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animal<\/jats:title><jats:p>A 16\u2010year\u2010old Fjord gelding with suspected pituitary pars intermedia dysfunction (<jats:styled-content style=\"fixed-case\">PPID<\/jats:styled-content>) was presented for evaluation of a nonpainful, firm and raised mass involving the lateral wing of the right nostril and the lip.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>Cytological examination of the mass showed marked pyogranulomatous inflammation and histopathological examination revealed a fungal mycetoma. Fungal culture identified the causative organism as <jats:italic>Aspergillus terreus<\/jats:italic>, which is not known for its propensity to cause either dermal granulomas or mycetoma in domestic animals. Further investigation, including a <jats:styled-content style=\"fixed-case\">TRH<\/jats:styled-content> stimulation test, led to a diagnosis of <jats:styled-content style=\"fixed-case\">PPID<\/jats:styled-content> (Cushing's disease), which may have led to immunosuppression of the animal and increased susceptibility to infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Clinical importance<\/jats:title><jats:p>The horse was treated medically with pergolide for the <jats:styled-content style=\"fixed-case\">PPID<\/jats:styled-content> and oral potassium iodide for the fungal infection, with good therapeutic response and no relapse after five months. Surgical debridement or excision was not performed. To the best of the authors\u2019 knowledge, this is the first case report of a cutaneous mycetoma caused by <jats:italic>A. terreus<\/jats:italic> in a horse.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12471","type":"journal-article","created":{"date-parts":[[2017,7,24]],"date-time":"2017-07-24T04:02:39Z","timestamp":1500868959000},"page":"629","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Successful medical treatment of an <i>Aspergillus terreus<\/i> mycetoma of the nostril\/lip in a 16\u2010year\u2010old Fjord pony gelding with pituitary pars intermedia dysfunction"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9832-4163","authenticated-orcid":false,"given":"Pia K.","family":"Randleff\u2010Rasmussen","sequence":"first","affiliation":[{"name":"VetAgro Sup, Veterinary Campus of Lyon University of Lyon 69280 Marcy l'Etoile France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7682-2452","authenticated-orcid":false,"given":"Marion","family":"Mosca","sequence":"additional","affiliation":[{"name":"VetAgro Sup, Veterinary Campus of Lyon University of Lyon 69280 Marcy l'Etoile France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Knoerr","sequence":"additional","affiliation":[{"name":"Cabinet V\u00e9t\u00e9rinaire du Vallon 465 route de la Merlanchonni\u00e8re 42740 St Paul en Jarez France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier","family":"Pin","sequence":"additional","affiliation":[{"name":"VetAgro Sup, Veterinary Campus of Lyon University of Lyon 69280 Marcy l'Etoile France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Desjardins","sequence":"additional","affiliation":[{"name":"VetAgro Sup, Veterinary Campus of Lyon University of Lyon 69280 Marcy l'Etoile France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,7,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.230.1.84"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90393-3"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4377-0920-9.00005-6"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2011.0712.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2001.62.1606"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2008.00719.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.217.707"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2006.00525.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2013.01.015"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cveq.2014.11.005"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/104063879500700429"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myv067"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/13693780802562092"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2012.08.003"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.41.12.5813-5816.2003"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0739(02)00018-4"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvde.12471","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12471","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T07:32:30Z","timestamp":1695713550000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,23]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1111\/vde.12471"],"URL":"https:\/\/doi.org\/10.1111\/vde.12471","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"type":"print","value":"0959-4493"},{"type":"electronic","value":"1365-3164"}],"subject":[],"published":{"date-parts":[[2017,7,23]]},"assertion":[{"value":"2017-06-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}