{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T08:25:14Z","timestamp":1740126314265,"version":"3.37.3"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T00:00:00Z","timestamp":1524528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Cutaneous adverse food reaction (<jats:styled-content style=\"fixed-case\">CAFR<\/jats:styled-content>) is diagnosed by performing an elimination diet trial utilizing prescription or home\u2010cooked diets followed by provocative challenge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To report findings of <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> analysis of a prescription vegetarian diet (<jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content>) for undeclared proteins of animal origin, as well as to describe its utilization for diagnosis and management of dogs suspected of having <jats:styled-content style=\"fixed-case\">CAFR<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Three client\u2010owned dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> analysis of <jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content> for 11 mammalian species and poultry. In three dogs, clinical examination, cytology, aerobic culture (if indicated) and at least one elimination diet trial with <jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In our case series, all dogs had a history of pruritus and recurrent pyoderma that resolved with infection control and an elimination diet trial. In cases 1 and 2, a diagnosis of <jats:styled-content style=\"fixed-case\">CAFR<\/jats:styled-content> was made following an elimination trial with <jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content> and provocative challenge. Case 3 had a previously confirmed diagnosis of <jats:styled-content style=\"fixed-case\">CAFR<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content> was successfully used to maintain remission of <jats:styled-content style=\"fixed-case\">CAFR<\/jats:styled-content>\u2010related signs. <jats:styled-content style=\"fixed-case\">PCR<\/jats:styled-content> testing of <jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content> was negative for 11 mammalian species and poultry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content> diet was found not to contain any undeclared mammalian or avian proteins. In this case series, the <jats:styled-content style=\"fixed-case\">RCV<\/jats:styled-content> was successfully used to diagnose and maintain three dogs with <jats:styled-content style=\"fixed-case\">CAFR<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12545","type":"journal-article","created":{"date-parts":[[2018,4,25]],"date-time":"2018-04-25T05:00:49Z","timestamp":1524632449000},"page":"345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>PCR<\/scp> analysis of a prescription vegetarian diet and use in three dogs with cutaneous adverse food reactions"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9734-5595","authenticated-orcid":false,"given":"Erin E.","family":"Aufox","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences University of Tennessee 2407 River Drive Knoxville TN 37996 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth R.","family":"May","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences University of Tennessee 2407 River Drive Knoxville TN 37996 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda A.","family":"Frank","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences University of Tennessee 2407 River Drive Knoxville TN 37996 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen A.","family":"Kania","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Diagnostic Sciences University of Tennessee Knoxville TN 37996 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.1411"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2009.00761.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3164.2003.00338.x"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2006.08.008"},{"key":"e_1_2_5_6_1","first-page":"297","article-title":"High molecular\u2010weight proteins in hydrolysed dog foods","volume":"26","author":"Roitel O","year":"2015","journal-title":"Vet Dermatol"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1067\/mai.2001.118515"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408390591001117"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2014.08.017"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12045"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12431"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jpn.12506"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2009.03.030"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvde.12545","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12545","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T02:36:04Z","timestamp":1695004564000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,24]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1111\/vde.12545"],"URL":"https:\/\/doi.org\/10.1111\/vde.12545","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"type":"print","value":"0959-4493"},{"type":"electronic","value":"1365-3164"}],"subject":[],"published":{"date-parts":[[2018,4,24]]},"assertion":[{"value":"2018-03-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-04-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}