{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:38:02Z","timestamp":1790689082503,"version":"4.1.0"},"reference-count":12,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,8,5]],"date-time":"2018-08-05T00:00:00Z","timestamp":1533427200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>There is a lack of controlled studies evaluating the efficacy of topical nonsteroidal agents for the treatment of canine atopic dermatitis (cAD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis\/Objectives<\/jats:title><jats:p>To compare the clinical efficacy of a commercial foam product (mousse), previously demonstrated to be effective in cAD (Foam A) with a foam\/mousse containing components from plant extracts (Foam B).<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Eight client\u2010owned dogs with nonseasonal mild\/moderate cAD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and materials<\/jats:title><jats:p>Dogs were treated twice weekly with either Foam A or Foam B for 14\u00a0days and after a wash\u2010out period of 14\u00a0days received the other foam in a randomized blinded study. Criteria evaluated included skin lesions [Canine Atopic Dermatitis Lesion Index (CADLI)], pruritus Visual Analog Scale (pVAS)], cosmetic evaluation and overall global product assessment by the owner and the investigator.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A significant improvement was noted for both treatment groups for both CADLI and pVAS scores (37.5% and 26.09%, respectively, for Foam A; 41.9% and 32.6%, respectively, for Foam B) (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a00.05). Owner and investigator evaluation of cosmetic characteristics of the products and global product assessment were positive for both mousses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and clinical relevance<\/jats:title><jats:p>The use of a foam may be useful in cAD to improve both skin lesions and pruritus. Both foams evaluated in this study were equally effective. This method of product delivery is easy to use for owners which is important to improve compliance in practice.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12675","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T07:35:21Z","timestamp":1533627321000},"page":"446","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Use of antipruritic and rehydrating foams on localized lesions of atopic dermatitis in dogs: a small\u2010scale pilot and comparative double\u2010blinded study"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0404-3185","authenticated-orcid":false,"given":"Emmanuel J.","family":"Bensignor","sequence":"first","affiliation":[{"name":"Dermatology Referral Service 6 rue mare pav\u00e9e 35510 Cesson\u2010S\u00e9vign\u00e9 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel J.","family":"Fabri\u00e8s","sequence":"additional","affiliation":[{"name":"Clinique v\u00e9t\u00e9rinaire La Croix du Sud 45 avenue de Toulouse 31650 Saint Orens de Gameville France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-015-0514-6"},{"key":"e_1_2_5_3_1","first-page":"39","article-title":"Treating atopic dermatitis: safety, efficacy and patient acceptability of a ceramide hyaluronic acid emollient foam","volume":"5","author":"Pacha O","year":"2012","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1473-2165.2011.00568.x"},{"key":"e_1_2_5_5_1","first-page":"49","article-title":"A multicenter randomized controlled single blinded study to evaluate the value of a new protocol with a shampoo and a foam to treat canine allergic dermatitis","volume":"48","author":"Bensignor E","year":"2013","journal-title":"Prat M\u00e9d Chir Anim Comp"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-015-0515-5"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2012.01113.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2008.00728.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12467"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1211\/jpp.62.06.0003"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2014.04.009"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11746-009-1483-3"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08643.x"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fvde.12675","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12675","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T04:05:59Z","timestamp":1694837159000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12675"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,5]]},"references-count":12,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["10.1111\/vde.12675"],"URL":"https:\/\/doi.org\/10.1111\/vde.12675","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,5]]},"assertion":[{"value":"2018-06-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-05","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}