{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:45:17Z","timestamp":1790624717795,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T00:00:00Z","timestamp":1551657600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Different sets of criteria are available in veterinary dermatology for the diagnosis of canine atopic dermatitis (c<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>); there are limited data to assess their reliability.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis\/Objectives<\/jats:title><jats:p>The aim of this study was to assess the discriminative and predictive ability of four sets in diagnosing c<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> in a population of dogs with different skin diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Two hundred and fifty dogs examined in the dermatology unit of a veterinary teaching hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and materials<\/jats:title><jats:p>Dogs were diagnosed with c<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>, flea infestation (<jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content>), flea bite hypersensitivity (<jats:styled-content style=\"fixed-case\">FBH<\/jats:styled-content>), sarcoptic mange (<jats:styled-content style=\"fixed-case\">SM<\/jats:styled-content>) and other skin diseases (<jats:styled-content style=\"fixed-case\">OD<\/jats:styled-content>). <jats:styled-content style=\"fixed-case\">FI<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> FBH<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SM<\/jats:styled-content> were pooled in one group of dermatoses mimicking c<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">MD<\/jats:styled-content>). All nonatopic dogs were grouped as a \u201cglobal population\u201d (<jats:styled-content style=\"fixed-case\">GP<\/jats:styled-content>). Four criteria sets were applied to all dogs. For each set of criteria, sensitivity, specificity, positive and negative predictive values (<jats:styled-content style=\"fixed-case\">PPV<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> NPV<\/jats:styled-content>), likelihood ratios (<jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>) and diagnostic odds ratio (<jats:styled-content style=\"fixed-case\">DOR<\/jats:styled-content>) were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>When applied to the <jats:styled-content style=\"fixed-case\">GP<\/jats:styled-content>, sensitivities ranged from 54 to 83%, specificities from 68 to 75% and <jats:styled-content style=\"fixed-case\">PPV<\/jats:styled-content>s from 35 to 43%. <jats:styled-content style=\"fixed-case\">NPV<\/jats:styled-content>s ranged from 87 to 94%. <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>s and <jats:styled-content style=\"fixed-case\">DOR<\/jats:styled-content>s were poor. When applied to <jats:styled-content style=\"fixed-case\">MD<\/jats:styled-content>, sensitivities remained unchanged, specificities and <jats:styled-content style=\"fixed-case\">PPV<\/jats:styled-content> were mildly higher, whereas <jats:styled-content style=\"fixed-case\">NPV<\/jats:styled-content>s were mildly lower and <jats:styled-content style=\"fixed-case\">LR<\/jats:styled-content>s and <jats:styled-content style=\"fixed-case\">DOR<\/jats:styled-content>s were comparable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>This study showed that each set of criteria had a low diagnostic reliability when used alone. The use of more discriminant criteria integrated into a thorough clinical approach excluding MDs should be considered.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12729","type":"journal-article","created":{"date-parts":[[2019,3,4]],"date-time":"2019-03-04T09:14:58Z","timestamp":1551690898000},"page":"188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Reliability of different sets of criteria in diagnosing canine atopic dermatitis applied to a population of 250 dogs seen in a veterinary teaching hospital"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0992-2848","authenticated-orcid":false,"given":"Thomas","family":"Br\u00e9ment","sequence":"first","affiliation":[{"name":"Unit Dermatology\/Parasitology\/Mycology School of Veterinary Medicine\u2010ONIRIS University of Nantes CS 40706, Route de Gachet 44307 Nantes Cedex 03 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