{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T13:32:52Z","timestamp":1775655172786,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T00:00:00Z","timestamp":1550448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Few studies have described the pathophysiology, clinical course, treatment outcomes and quality of life (QoL) of cats with pemphigus foliaceus (<jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>Describe clinicopathological features, treatment outcomes and impacts on QoL in feline<jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Forty\u2010nine client\u2010owned cats with<jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>that presented to a veterinary teaching hospital between 1987 and 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and materials<\/jats:title><jats:p>Medical records and histopathological reports were reviewed to obtain clinicopathological data and treatment outcomes. Owners were contacted and requested to complete a questionnaire to obtain long\u2010term follow\u2010up and evaluate the impacts of<jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>on QoL of cats and owners.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Domestic short\/medium\/long hair breeds were most commonly affected, with pinnae, head, haired face, nasal planum and ungual folds most frequently involved. Associated pruritus and systemic signs of illness were common. Vasculopathological changes were noted in a small proportion of cats. Corticosteroid monotherapy was sufficient to induce complete remission in the majority of cats. Pemphigus foliaceus and its management had a negative impact on QoL of both cats and owners. Receiving\/administering medications, attending veterinary appointments, and financial and time commitments were cited sources of stress for affected cats and\/or owners.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>Results illustrate that affected cats generally respond favourably to treatment but do require long\u2010term therapy. The exact aetiology of the vasculopathological changes was unclear; it may reflect the stage or severity of disease or suggest the presence of a cutaneous adverse drug reaction. Clinicians managing cats with<jats:styled-content style=\"fixed-case\">PF<\/jats:styled-content>should be aware of the potential negative impact on QoL of owners and cats and adjust management accordingly.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12731","type":"journal-article","created":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T08:26:22Z","timestamp":1550564782000},"page":"209","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Clinicopathological findings and clinical outcomes in 49 cases of feline pemphigus foliaceus examined in Northern California, USA (1987\u20132017)"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6833-0167","authenticated-orcid":false,"given":"Tyler J.M.","family":"Jordan","sequence":"first","affiliation":[{"name":"William R. 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