{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T05:35:50Z","timestamp":1757309750584,"version":"3.40.5"},"reference-count":11,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T00:00:00Z","timestamp":1564531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Erysipelothrix rhusiopathiae<\/jats:italic> is a widespread Gram\u2010positive, nonsporulating rod bacterium predominantly associated with skin disease in swine and cetaceans. Cutaneous lesions have yet to be described in dogs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the clinical presentation, molecular and histopathological diagnosis, and treatment of a case of erysipeloid caused by <jats:italic>E.\u00a0rhusiopathiae<\/jats:italic> in a dog.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>A 6\u2010month\u2010old spayed female standard poodle dog presented with lethargy, fever, vomiting and diarrhoea. Skin lesions appeared 20\u00a0days post first examination.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and materials<\/jats:title><jats:p>Complete blood count, serum chemistry profile, urinalysis, urine culture, blood culture, computed topography, forelimb radiography, joint and cerebrospinal fluid aspiration were performed; samples were collected for skin cytological evaluation, culture and histopathological analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Blood cultures yielded Gram\u2010positive, catalase\u2010negative bacilli. Histopathological evaluation of skin biopsies revealed lymphoplasmacytic, neutrophilic and histiocytic perivascular and periadnexal dermatitis, and vasculitis. Cutaneous and blood PCR and sequencing of 16S rRNA identified the bacteria as <jats:italic>E.\u00a0rhusiopathiae<\/jats:italic>. Clinical resolution was observed following the use of of amoxicillin\/clavulanic acid and ciprofloxacin therapies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical importance<\/jats:title><jats:p>To the best of the authors\u2019 knowledge, this is the first confirmed case of erysipeloid caused by <jats:italic>E.\u00a0rhusiopathiae<\/jats:italic> in a dog. Clinical resolution was attained with the extended use of antibiotics. After 13\u00a0months, no clinical signs had returned.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12773","type":"journal-article","created":{"date-parts":[[2019,7,31]],"date-time":"2019-07-31T08:59:39Z","timestamp":1564563579000},"page":"434","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Erysipeloid lesions caused by <i>Erysipelothrix rhusiopathiae<\/i> in a dog: clinical and histopathological findings, molecular diagnosis and treatment"],"prefix":"10.1111","volume":"30","author":[{"given":"Kalie R.","family":"Marshall","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida 2015 SW 16th Avenue PO Box 100126 Gainesville FL 32611 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9378-7257","authenticated-orcid":false,"given":"Stuart A.","family":"Walton","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida 2015 SW 16th Avenue PO Box 100126 Gainesville FL 32611 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"Boyd","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida 2015 SW 16th Avenue PO Box 100126 Gainesville FL 32611 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradley","family":"Bishop","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida 2015 SW 16th Avenue PO Box 100126 Gainesville FL 32611 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Wellehan","sequence":"additional","affiliation":[{"name":"Department of Comparative, Diagnostic and Population Medicine College of Veterinary Medicine University of Florida 2015 SW 16th Avenue PO Box 100126 Gainesville FL 32611 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Craft","sequence":"additional","affiliation":[{"name":"Department of Comparative, Diagnostic and Population Medicine College of Veterinary Medicine University of Florida 2015 SW 16th Avenue PO Box 100126 Gainesville FL 32611 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4893-4289","authenticated-orcid":false,"given":"Domenico","family":"Santoro","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences College of Veterinary Medicine University of Florida 2015 SW 16th Avenue PO Box 100126 Gainesville FL 32611 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,31]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_4_2_1","DOI":"10.1016\/j.vetmic.2009.08.012"},{"doi-asserted-by":"publisher","key":"e_1_2_4_3_1","DOI":"10.1099\/00222615-48-9-789"},{"doi-asserted-by":"publisher","key":"e_1_2_4_4_1","DOI":"10.1111\/j.1365-2230.2009.03444.x"},{"doi-asserted-by":"publisher","key":"e_1_2_4_5_1","DOI":"10.1111\/j.1365-3164.2012.01115.x"},{"doi-asserted-by":"publisher","key":"e_1_2_4_6_1","DOI":"10.3415\/VCOT-09-05-0058"},{"doi-asserted-by":"publisher","key":"e_1_2_4_7_1","DOI":"10.1186\/1751-0147-46-159"},{"doi-asserted-by":"publisher","key":"e_1_2_4_8_1","DOI":"10.1155\/2013\/474593"},{"key":"e_1_2_4_9_1","first-page":"373","volume-title":"Robbins and Cotran Pathologic Basis Of Disease","author":"Kumar V","year":"2005"},{"unstructured":"JPC Systemic Pathology website.Integumentary system I\u2010B08 September2016. 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