{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T19:50:33Z","timestamp":1788551433420,"version":"build-2803163510"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T00:00:00Z","timestamp":1575244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2020,6]]},"abstract":"Background<\/jats:title>It has long been speculated that sterile granulomatous dermatitis and lymphadenitis (SGDL) occurs in adult dogs. However, only three published case reports exist.<\/jats:p><\/jats:sec>Hypothesis\/objectives<\/jats:title>To describe clinical presentation, identify breed predispositions, and assess treatment and outcomes of adult dogs with the histopathological diagnosis of SGDL.<\/jats:p><\/jats:sec>Animals<\/jats:title>Included are 90 dogs with biopsies submitted to a veterinary teaching hospital with a histopathological diagnosis consistent with SGDL, from 2004 to 2018, of which 35 had medical records available for review.<\/jats:p><\/jats:sec>Methods<\/jats:title>Data were analysed retrospectively from histopathology submission forms, medical records, surveys and telephone calls. Scoring systems were created to aid statistical analysis of outcomes.<\/jats:p><\/jats:sec>Results<\/jats:title>Havanese dog (P\u00a0<\/jats:italic><\u00a00.0001), Australian shepherd dog (P\u00a0<\/jats:italic><\u00a00.0001), Irish setter (P<\/jats:italic>\u00a0<\u00a00.0001), Dachshund (P<\/jats:italic>\u00a0=\u00a00.0002), bichon frise (P<\/jats:italic>\u00a0=\u00a00.0003) and Maltese dog (P<\/jats:italic>\u00a0=\u00a00.004) were significantly over\u2010represented breeds. The median age at onset was 1,292 days (3.54\u00a0years). Dogs up to five years of age were significantly over\u2010represented (P<\/jats:italic>\u00a0<\u00a00.01). Of 35 dogs with medical records available for review, the median treatment duration was 60\u00a0days and the median time to remission 28\u00a0days. Remission status was not established for five dogs but the remaining 30 dogs reached remission. Nineteen dogs remained in complete remission. Recrudescence occurred in 11 dogs (median follow\u2010up 60 days).<\/jats:p><\/jats:sec>Conclusions and clinical importance<\/jats:title>This study shows a close parallel in clinical appearance, histopathological results and clinical behaviour, of both adult and juvenile onset SGDL; therefore, SGDL should be considered as a differential diagnosis for dogs of all ages.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12820","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T23:04:29Z","timestamp":1575327869000},"page":"219","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Sterile granulomatous dermatitis and lymphadenitis (juvenile cellulitis) in adult dogs: a retrospective analysis of 90 cases (2004\u20132018)"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9159-1683","authenticated-orcid":false,"given":"Allison","family":"Inga","sequence":"first","affiliation":[{"name":"Red Bank Veterinary Hospital 197 Hance Ave Tinton Falls NJ 07724 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory C.","family":"Griffeth","sequence":"additional","affiliation":[{"name":"Red Bank Veterinary Hospital 197 Hance Ave Tinton Falls NJ 07724 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth J.","family":"Drobatz","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine Department of Clinical Studies University of Pennsylvania 3900 Spruce Street Philadelphia PA 19104 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle H.","family":"Goldschmidt","sequence":"additional","affiliation":[{"name":"Opus College of Business University of St. Thomas 1000 Lasalle Ave Minneapolis MN 55403 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4718-6071","authenticated-orcid":false,"given":"Elizabeth A.","family":"Mauldin","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine Department of Pathobiology University of Pennsylvania 3900 Spruce Street Philadelphia PA 19104 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/9780470752487","volume-title":"Skin Diseases of the Dog and Cat, Clinical and histopathologic diagnosis","author":"Gross TL","year":"2005"},{"key":"e_1_2_6_3_1","first-page":"708","volume-title":"Muller and Kirk's Small Animal Dermatology","author":"Miller WH","year":"2013"},{"key":"e_1_2_6_4_1","first-page":"1,609","article-title":"Juvenile cellulitis in dogs: 15 cases (1979\u20131988)","volume":"195","author":"White SD","year":"1989","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.124.24.642-a"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/030098588902600606"},{"key":"e_1_2_6_7_1","first-page":"1,265","article-title":"Combination of cyclosporin A and prednisolone for juvenile cellulitis concurrent with hindlimb paresis in 3 English cocker spaniel puppies","volume":"51","author":"Park C","year":"2010","journal-title":"Can Vet J"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-5317-7.00006-0"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-31-3-204"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2004.tb00232.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2005.tb12738.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2004.tb00238.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12517"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2010.00942.x"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12820","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vde.12820","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,7]],"date-time":"2023-09-07T07:14:12Z","timestamp":1694070852000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,2]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1111\/vde.12820"],"URL":"https:\/\/doi.org\/10.1111\/vde.12820","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,2]]},"assertion":[{"value":"2019-07-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}