{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T02:06:40Z","timestamp":1747188400724,"version":"3.40.5"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T00:00:00Z","timestamp":1611014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000098","name":"NIH Clinical Center","doi-asserted-by":"publisher","award":["AR056635"],"award-info":[{"award-number":["AR056635"]}],"id":[{"id":"10.13039\/100000098","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>R\u00e9sum\u00e9<\/jats:title><jats:sec><jats:title>Contexte<\/jats:title><jats:p>Une nouvelle anomalie cong\u00e9nitale de la tige pilaire ressemblant au ph\u00e9notype nu des rongeurs est d\u00e9crite dans une port\u00e9e de quatre chats europ\u00e9ens (DSH). Les donn\u00e9es relatives aux anomalies de la tige pilaire et des follicules pileux sont rares en m\u00e9decine v\u00e9t\u00e9rinaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectifs<\/jats:title><jats:p>D\u00e9crire et comparer les anomalies structurelles de ces chats avec d\u2019autres dystrophies f\u00e9lines et d\u2019autres mammif\u00e8res.<\/jats:p><\/jats:sec><jats:sec><jats:title>Sujets<\/jats:title><jats:p>Une port\u00e9e de chats DSH avec alop\u00e9cie progressive non\u2010inflammatoire.<\/jats:p><\/jats:sec><jats:sec><jats:title>M\u00e9thodes<\/jats:title><jats:p>L\u2019\u00e9valuation histopathologique, la microscopie \u00e9lectronique \u00e0 transmission et l\u2019analyse des \u00e9l\u00e9ments par rayons X d\u00e9finissaient les changements pilaires et cutan\u00e9s des chats n\u00e9s alop\u00e9ciques. Les donn\u00e9es ont \u00e9t\u00e9 compar\u00e9es aux archives de chats normaux et de souris mutantes <jats:italic>Dsg4<\/jats:italic><jats:italic><jats:sup>lahJ<\/jats:sup><\/jats:italic> et <jats:italic>Krt75<\/jats:italic><jats:italic><jats:sup>tm1Der<\/jats:sup><\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>R\u00e9sultats<\/jats:title><jats:p>La microscopie \u00e9lectronique \u00e0 lumi\u00e8re et \u00e0 balayage des poils a r\u00e9v\u00e9l\u00e9 des d\u00e9fauts de forme de l\u2019extr\u00e9mit\u00e9 de la tige pilaire en pointe ou en lance. Les donn\u00e9es histopathologiques consistaient en des tiges pilaires enfl\u00e9es, initialement au dessus de la matrice du bulbe pilaire et ensuite retrouv\u00e9 dans les parties distales des follicules pileux t\u00e9log\u00e8nes, semblables \u00e0 ceux observ\u00e9s chez les souris mutantes <jats:italic>Dsg4<\/jats:italic><jats:italic><jats:sup>lahJ<\/jats:sup><\/jats:italic> <jats:italic>Krt75<\/jats:italic><jats:italic><jats:sup>tm1Der<\/jats:sup><\/jats:italic> . La microscopie \u00e9lectronique \u00e0 transmission de la tige pilaire et des follicules pileux a r\u00e9v\u00e9l\u00e9 une perte de la structure normale des poils de garde chez les chats alop\u00e9ciques. Il y a avait une diminution statistiquement significative du contenu en sulfure juste au dessous des d\u00e9fauts des tiges pilaires (trichothiodystrophie).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions et importance Clinique<\/jats:title><jats:p>une forme rare d\u2019alop\u00e9cie cong\u00e9nitale r\u00e9sultant en une dystrophie folliculaire est d\u00e9crite chez le chat, comparable aux changements de la tige pilaire et du follicule pileux d\u00e9crits dans plusieurs souches de souris mutantes avec une mutation g\u00e9n\u00e9tique unique des g\u00e8nes des mol\u00e9cules d\u2019adh\u00e9sion ou de k\u00e9ratine.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12925","type":"journal-article","created":{"date-parts":[[2021,1,20]],"date-time":"2021-01-20T01:29:01Z","timestamp":1611106141000},"page":"74","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hair follicle dystrophy in a litter of domestic cats resembling lanceolate hair mutant mice"],"prefix":"10.1111","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1940-0341","authenticated-orcid":false,"given":"Ana","family":"Rostaher","sequence":"first","affiliation":[{"name":"Centre for Clinical Veterinary Medicine Ludwig\u2010Maximilian University Munich  Veterin\u00e4rstrasse 13 M\u00fcnchen 80539 Germany"},{"name":"Dermatology Unit Clinic for Small Animal Internal Medicine Vetsuisse Faculty University of Zurich  Winterthurerstrasse 260 Zurich 8057 Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonya","family":"Bettenay","sequence":"additional","affiliation":[{"name":"Tierdermatologie Deisenhofen  Sch\u00e4ftlarner Weg 1A Oberhaching 82041 Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Specht","sequence":"additional","affiliation":[{"name":"Centre for Clinical Veterinary Medicine Ludwig\u2010Maximilian University Munich  Veterin\u00e4rstrasse 13 M\u00fcnchen 80539 Germany"},{"name":"Tier\u00e4rztliche Klinik N\u00fcrnberg Hafen  Wertachstra\u00dfe 1 N\u00fcrnberg 90451 Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen A.","family":"Silva","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory  600 Main Street Bar Harbor ME 04609 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lesley","family":"Bechtold","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory  600 Main Street Bar Harbor ME 04609 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Dermatology Charles C. Gates Regenerative Medicine and Stem Cell Biology Program University of Colorado at Denver and Health Sciences Center  12800 East 19th Avenue Aurora CO 80045 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monir","family":"Majzoub","sequence":"additional","affiliation":[{"name":"Institute for Veterinary Pathology Ludwig\u2010Maximilian University Munich  Veterin\u00e4rstrasse 13 M\u00fcnchen 80539 Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5835-5910","authenticated-orcid":false,"given":"Ralf S.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Centre for Clinical Veterinary Medicine Ludwig\u2010Maximilian University Munich  Veterin\u00e4rstrasse 13 M\u00fcnchen 80539 Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Sundberg","sequence":"additional","affiliation":[{"name":"The Jackson Laboratory  600 Main Street Bar Harbor ME 04609 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,1,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/9780203490662"},{"key":"e_1_2_6_3_1","first-page":"91","volume-title":"Disorders of hair growth","author":"Whiting DA","year":"1994"},{"volume-title":"Pathology of Genetically Engineered and Other Mice","author":"Sundberg JP","key":"e_1_2_6_4_1","doi-asserted-by":"crossref","DOI":"10.1002\/9781119624608"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00273-3"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1087-0024.2005.10110.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5701038"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2015.01.015"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1162525"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00335-010-9290-6"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.1996.tb00252.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1986.tb02126.x"},{"key":"e_1_2_6_13_1","first-page":"506","article-title":"Hairless cats in Great Britain","volume":"75","author":"Hendy\u2010Ibbs PM","year":"1984","journal-title":"J Hered"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12004"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2005.00492.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1989.tb01457.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2004.23442.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1984.tb04659.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1980.01640360049017"},{"volume-title":"Pathology of Genetically Engineered Mice and Other Mutants","author":"Sundberg JP","key":"e_1_2_6_20_1","doi-asserted-by":"crossref","DOI":"10.1002\/9781119624608"},{"key":"e_1_2_6_21_1","first-page":"53","volume-title":"McKee's pathology of the skin","author":"Metze D","year":"2020"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12297438"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.2000.009003206.x"},{"key":"e_1_2_6_24_1","first-page":"121","volume-title":"Systemic approach to evaluation of mouse mutations","author":"Bechtold LS","year":"2000"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.52"},{"key":"e_1_2_6_26_1","doi-asserted-by":"crossref","first-page":"1,985","DOI":"10.1242\/jcs.107.7.1985","article-title":"Ultrastructural visualization of cross\u2010linked protein features in epidermal appendages","volume":"107","author":"Rice RH","year":"1994","journal-title":"J Cell Sci"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0185(19990201)254:2<231::AID-AR9>3.0.CO;2-6"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/jhered\/esg011"},{"key":"e_1_2_6_29_1","first-page":"93","volume-title":"Hair Loss Disorders in Domestic Animals","author":"Mecklenburg L","year":"2009"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1001380"},{"key":"e_1_2_6_31_1","first-page":"327","article-title":"Border disease of sheep and goats","volume":"29","author":"Nettleton PF","year":"1998","journal-title":"Vet Rec"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.92.1.15"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05659"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.291"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-genom-021610-131501"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700384"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12925","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vde.12925","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.12925","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T10:57:16Z","timestamp":1693565836000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.12925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,19]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/vde.12925"],"URL":"https:\/\/doi.org\/10.1111\/vde.12925","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"type":"print","value":"0959-4493"},{"type":"electronic","value":"1365-3164"}],"subject":[],"published":{"date-parts":[[2021,1,19]]},"assertion":[{"value":"2020-10-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}