{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:53Z","timestamp":1787875253439,"version":"build-2784847793"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T00:00:00Z","timestamp":1624320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Canine demodicosis is a common disease in small animal practice. Although a number of studies evaluating treatment efficacy for canine demodicosis have used clinical scoring systems, none have been validated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study evaluated the validity, reliability, reproducibility and sensitivity to change of a clinical scoring system for canine demodicosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and materials<\/jats:title><jats:p>Fifty\u2010eight dogs with generalised demodicosis were evaluated using a clinical scoring system that assessed erythema, comedones\/ papules\/pustules, follicular casts\/scales\/crusts and alopecia, rated from none to mild, moderate and severe in 36 body locations. Two evaluators scored lesions at monthly consecutive visits during treatment. Mites were counted to a maximum of 50 in four deep skin scrapings. With &gt;50 mites, the approximate mite number was calculated with the help of a grid drawn onto the slide before placing the scraped material onto it.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A Pearson correlation coefficient showed a high interobserver reliability (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.97) between two different clinicians evaluating the same dog. The Wilcoxon signed rank test showed good sensitivity to change with a reduction of clinical scores with each of the first six evaluations (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001). A linear mixed model also showed a clear reduction in mite counts (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and clinical scores (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.0001) from the first evaluation with time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion and clinical relevance<\/jats:title><jats:p>The clinical scoring system for canine demodicosis evaluated in this study showed a good sensitivity to change and interobserver reliability, and can be used in studies evaluating canine demodicosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.12980","type":"journal-article","created":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T03:11:57Z","timestamp":1624417917000},"page":"311","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Evaluation of a clinical scoring system for canine 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