{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T02:41:20Z","timestamp":1783996880364,"version":"3.55.0"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T00:00:00Z","timestamp":1658448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Little information has been published regarding treatment of canine anal sacculitis (AS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Primary objective: determine the outcomes of AS local treatment at the referral dermatology service of the authors' institution. Secondary objective: determine signalment, body condition score (BCS), stool quality and comorbidities associated with AS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Thirty\u2010three dogs with AS presented to the referral dermatology service between 1 January 2010 and 31 March 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>An electronic medical record search was conducted. Information regarding sex, breed, age at disease onset, weight, BCS, stool quality, comorbidities, treatment and treatment outcome were collected. Treatment outcome was categorised as \u201cresolved clinically\u201d, \u201cclinical signs resolved per owner\u201d, \u201cdid not complete treatment\u201d or \u201cfailed\u201d. Dogs were excluded if seen by another service, not treated for AS, or if perianal sinuses (fistulae), anal sac masses, or anal sac abscesses were identified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen dogs were male and 14 female. Twenty\u2010four breeds were included. Average age at disease onset was 4.4\u2009years. Average BCS was 5.8 of 9. Stool quality was \u201cpoor\u201d in seven of 33 and normal in 23 of 33 cases. Atopic dermatitis was the most common comorbidity (12 of 33). Treatment typically consisted of anal sac flushing with saline followed by infusion using a commercially available steroid\/antibiotic\/antifungal ointment. Treatment was repeated on average 2.9 times. Resolution of AS was obtained in 24 of 33 cases, clinical signs resolved per owner in four of 33, five of 33 cases did not complete treatment, and no cases failed treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and clinical relevance<\/jats:title><jats:p>Local treatment with flushing and infusion is effective for treating AS in dogs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.13102","type":"journal-article","created":{"date-parts":[[2022,7,22]],"date-time":"2022-07-22T09:13:02Z","timestamp":1658481182000},"page":"426-434","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Local treatment for canine anal sacculitis: A retrospective study of 33 dogs"],"prefix":"10.1111","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9043-6662","authenticated-orcid":false,"given":"Annette","family":"Lundberg","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences University of Minnesota College of Veterinary Medicine  St Paul MN USA"},{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3944-1597","authenticated-orcid":false,"given":"Sandra N.","family":"Koch","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Auburn University College of Veterinary Medicine  Auburn AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila M.F.","family":"Torres","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences University of Minnesota College of Veterinary Medicine  St Paul MN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,7,22]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"573","article-title":"Incidence distribution of anal sac disease in the dog","volume":"10","author":"Harvey CE","year":"1974","journal-title":"J Am Anim Hosp Assoc"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani12010095"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/vetr.203"},{"key":"e_1_2_8_5_1","first-page":"31","article-title":"Anal sacs: a new approach to an old problem?","author":"Paterson S","year":"2016","journal-title":"Vet Pract"},{"key":"e_1_2_8_6_1","first-page":"122","article-title":"Anal sacculitis refractory to standard treatment","volume":"106","author":"Bloom P.","year":"2011","journal-title":"Vet Med"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1976.tb06996.x"},{"key":"e_1_2_8_8_1","first-page":"312","article-title":"Diet and anal\u2010sac impaction in dogs","volume":"12","author":"Beynen AC","year":"2019","journal-title":"Dier\u2010en\u2010Arts"},{"key":"e_1_2_8_9_1","first-page":"104","article-title":"Novel fiber\u2010rich supplement effective for prevention and treatment of acute, episodic and chronic anal gland disease in dogs and cats","volume":"1","author":"Ehrenzweig J.","year":"2018","journal-title":"Int J Vet Anim Med"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1976.tb06930.x"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1935(05)80155-1"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1995.tb02756.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2010.00916.x"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.2004.00629.x"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2003.tb11418.x"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3164.2002.00310.x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.5187\/jast.2019.61.6.366"},{"key":"e_1_2_8_18_1","first-page":"214","article-title":"Treatment of anal sacculitis in dogs","volume":"83","author":"Durmus AS","year":"2006","journal-title":"Indian Vet J"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1976.tb06997.x"},{"key":"e_1_2_8_20_1","first-page":"36","article-title":"The comparative anatomy and pathology of anal glands. Arris and Gale lecture delivered at the Royal College of Surgeons of England on 25th February 1965","volume":"40","author":"McColl I.","year":"1967","journal-title":"Ann R Coll Surg Engl"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1976.tb06931.x"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.13102","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/vde.13102","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.13102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T16:23:19Z","timestamp":1692807799000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.13102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,22]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1111\/vde.13102"],"URL":"https:\/\/doi.org\/10.1111\/vde.13102","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,22]]},"assertion":[{"value":"2022-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}