{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T06:23:16Z","timestamp":1770963796835,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T00:00:00Z","timestamp":1679875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>There are limited clinical studies evaluating the <jats:italic>Trichophyton mentagrophytes<\/jats:italic> complex, with most reports confined to small case studies. Additionally, the studies are dated and provide limited information on response to newer or currently available therapies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis\/Objectives<\/jats:title><jats:p>The aim of the study was to determine if there is a breed prevalence, lesion distribution and seasonality associated with the <jats:italic>T.\u00a0mentagrophytes<\/jats:italic> complex for dogs evaluated in the central United States. An additional aim of the study was to evaluate response to therapies because there are minimal data available on clinical response with newer systemic antifungal drugs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>A total of 64 canine medical records were evaluated that had a previous diagnosis of <jats:italic>T.\u00a0mentagrophytes<\/jats:italic> complex infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>A retrospective study of medical records to evaluate signalment, time of onset of clinical signs, clinical presentation and therapeutic management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A higher incidence of <jats:italic>T.\u00a0mentagrophytes<\/jats:italic> complex infection was observed in the American Kennel Club (AKC) Sporting group (43%) and Terrier group (20%). A seasonal influence was noted, with the onset of clinical signs being highest in October. Lesions most often affected the muzzle (48%), followed by the head excluding the pinnae (21%). Ketoconazole, itraconazole and terbinafine appeared equivalent as systemic therapeutic options to treat <jats:italic>T.\u00a0mentagrophytes<\/jats:italic> complex infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Clinical Relevance<\/jats:title><jats:p>This study identified patterns in breeds, seasonality and lesion distribution for the <jats:italic>T.\u00a0mentagrophytes<\/jats:italic> complex in dogs from the central United States. Additionally, the study found several reasonable and reliable treatment options for systemic therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.13160","type":"journal-article","created":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T06:22:50Z","timestamp":1679984570000},"page":"310-317","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Trichophyton mentagrophytes<\/i> complex: A retrospective study of 64 dogs from the Central United States (1997\u20132020)"],"prefix":"10.1111","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6098-4887","authenticated-orcid":false,"given":"Jason B.","family":"Pieper","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences Iowa State University  Ames Iowa USA"},{"name":"Department of Veterinary Clinical Medicine University of Illinois  Urbana Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel 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