{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T04:06:18Z","timestamp":1763179578301,"version":"3.30.2"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T00:00:00Z","timestamp":1718668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012895","name":"Zoetis","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012752","name":"Elanco Animal Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012752","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022822","name":"Merck Animal Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022822","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The SCORing Feline Allergic Dermatitis scale (SCORFAD) is a validated dermatological scale assessing reaction patterns associated with allergic dermatitis in cats. While no pathognomonic reaction pattern is recognised with flea allergy dermatitis (FAD), miliary dermatitis is more common.<\/jats:p><\/jats:sec><jats:sec><jats:title>Hypothesis\/Objective<\/jats:title><jats:p>This study aimed to document regional cutaneous reaction patterns of cats with fleas using a modified SCORFAD (mSCORFAD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>In total, 142 owned cats from West Central Florida enrolled over three study periods. To be included, each cat and household environment had five or more fleas on Day (D)0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Cats were examined on D0, D7, D14, D21, D28, D44, D56 and D80. On D0 they were treated with an isoxazoline and treatment continued through the study. Ten body regions were assessed using mSCORFAD to give a regional score for each of four reaction patterns. These were compared using the Wilcoxon rank sum test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At D80 there was an 80% reduction in total mSCORFAD representing clinical response to ectoparasite control only. The most commonly affected region was the ventral abdomen with a mean mSCORFAD score of 1.8 (95% confidence interval\u2009=\u20091.5\u20132.1) compared with other body regions (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). The most common reaction patterns were self\u2010induced alopecia on the ventral abdomen and miliary dermatitis in the cervical region (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions and Clinical Relevance<\/jats:title><jats:p>The mSCORFAD suggests that self\u2010induced alopecia on the ventral abdomen and miliary dermatitis in the cervical region is more strongly associated with a flea burden in cats.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vde.13275","type":"journal-article","created":{"date-parts":[[2024,6,18]],"date-time":"2024-06-18T09:09:19Z","timestamp":1718701759000},"page":"508-515","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Use of a modified SCORFAD scale to define localised reaction patterns associated with a flea burden in cats"],"prefix":"10.1111","volume":"35","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1454-563X","authenticated-orcid":false,"given":"Bridgette","family":"Sampeck","sequence":"first","affiliation":[{"name":"Animal Dermatology South  New Port Richey Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cameron","family":"Sutherland","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Kansas State University  Manhattan Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S.","family":"Canfield","sequence":"additional","affiliation":[{"name":"Animal Dermatology South  New Port Richey Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian H.","family":"Herrin","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine Kansas State University  Manhattan Kansas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,18]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_10_2_1","DOI":"10.1111\/vde.12935"},{"doi-asserted-by":"publisher","key":"e_1_2_10_3_1","DOI":"10.1111\/j.1365-3164.2011.00962.x"},{"doi-asserted-by":"publisher","key":"e_1_2_10_4_1","DOI":"10.1111\/j.1365-3164.2012.01071.x"},{"doi-asserted-by":"publisher","key":"e_1_2_10_5_1","DOI":"10.1111\/vde.12253"},{"doi-asserted-by":"publisher","key":"e_1_2_10_6_1","DOI":"10.1111\/j.1365-3164.2012.01092.x"},{"key":"e_1_2_10_7_1","first-page":"627","volume-title":"Muller and Kirk's small animal dermatology","author":"Scott DW","year":"2001"},{"doi-asserted-by":"publisher","key":"e_1_2_10_8_1","DOI":"10.1186\/s12917-019-2081-8"},{"doi-asserted-by":"publisher","key":"e_1_2_10_9_1","DOI":"10.1016\/j.vetpar.2020.109172"},{"doi-asserted-by":"publisher","key":"e_1_2_10_10_1","DOI":"10.1016\/j.vpoa.2019.100009"},{"unstructured":"SutherlandC TomlinsonT WilsonG GrayA MillerK GinT et\u00a0al.Assessment of Credelio\u00ae CAT (lotilaner) and Credelio\u00ae (lotilaner) for control of in\u2010home Ctenocephalides felis infestations. 68th annual meeting of the American Association of Veterinary Parasitologists. Lexington KY. June 10\u201313th 2023. [Abstract].2023.","key":"e_1_2_10_11_1"},{"volume-title":"R: a language and environment for statistical computing","year":"2021","author":"R Core Team","key":"e_1_2_10_12_1"},{"doi-asserted-by":"publisher","key":"e_1_2_10_13_1","DOI":"10.1111\/vde.13003"},{"doi-asserted-by":"publisher","key":"e_1_2_10_14_1","DOI":"10.1603\/0022-2585-39.4.685"},{"doi-asserted-by":"publisher","key":"e_1_2_10_15_1","DOI":"10.1002\/9781118738818.ch39"},{"key":"e_1_2_10_16_1","first-page":"S29","article-title":"Correlation of feline IgE, determined by Fc\u03b5 RI\u03b1\u2010based ELISA technology, and IDST to Ctenocephalides felis salivary antigens in a feline model of flea bite allergic dermatitis","volume":"19","author":"McCall CA","year":"1997","journal-title":"Comp Cont Ed Pract Vet"},{"doi-asserted-by":"publisher","key":"e_1_2_10_17_1","DOI":"10.1016\/S1098-612X(03)00026-3"},{"doi-asserted-by":"publisher","key":"e_1_2_10_18_1","DOI":"10.1007\/s00436-006-0163-6"},{"doi-asserted-by":"publisher","key":"e_1_2_10_19_1","DOI":"10.1007\/s00436-003-0914-6"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.13275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T12:36:36Z","timestamp":1734611796000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.13275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,18]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1111\/vde.13275"],"URL":"https:\/\/doi.org\/10.1111\/vde.13275","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"type":"print","value":"0959-4493"},{"type":"electronic","value":"1365-3164"}],"subject":[],"published":{"date-parts":[[2024,6,18]]},"assertion":[{"value":"2023-11-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}