{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:18:24Z","timestamp":1789690704186,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Suppurative\n                      <jats:italic>Malassezia<\/jats:italic>\n                      otitis externa (SMO) is a rare, severe presentation of\n                      <jats:italic>Malassezia<\/jats:italic>\n                      otitis (MO) sparsely reported in the literature.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>\n                      The primary objective of this study was to describe the clinical presentation, diagnostic findings, treatment, and prognosis of SMO. A secondary objective was to speciate available SMO isolates, as this phenotype may be caused by different\n                      <jats:italic>Malassezia<\/jats:italic>\n                      species.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Nine client\u2010owned dogs with SMO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A retrospective study of medical records from nine dogs with SMO diagnosed at an academic referral hospital from 2022 to 2024. Three SMO and 10 MO isolates from poodle\u2010crosses were speciated with matrix\u2010assisted laser desorption and ionisation time\u2010of\u2010flight mass spectrometry (MALDI\u2010TOF MS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Young (average 1\u2010year\u2010old), male (67%), poodle or poodle\u2010crosses (67%; six of nine dogs) were most often affected. Clinical presentation included unilateral otitis externa (77%; seven of nine dogs) with dark brown mucoid discharge, canal ulceration, erythema and glandular hyperplastic changes (100%). Cytological findings included yeast, neutrophils, and extracellular material suggestive of biofilm (100%). Prior otic treatment was primarily misdirected towards\n                      <jats:italic>Pseudomonas<\/jats:italic>\n                      otitis.\n                      <jats:italic>Malassezia pachydermatis<\/jats:italic>\n                      was identified in two SMO isolates and half of the MO isolates. Prednisone (0.5\u20131\u2009mg\/kg\/day) per os daily tapered over 1\u2009month plus daily otic orbifloxacin, mometasone furoate monohydrate and posaconazole (Posatex; Merck Animal Health) achieved complete resolution in 83% of affected ears without an anaesthetised otic lavage. At the time of writing, there was no known recurrence of any case within at least 6\u2009months of treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Relevance<\/jats:title>\n                    <jats:p>SMO is a phenotypically severe presentation of MO clinically mimicking suppurative bacterial otitis. Young, male poodle\u2010crosses are commonly affected. Ear canal hair plucking is likely to incite severe primary inflammation before SMO development.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vde.13372","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T04:15:19Z","timestamp":1752812119000},"page":"889-902","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Suppurative\n                    <i>Malassezia<\/i>\n                    Otitis Externa: Clinical Features, Treatment, and Preliminary Isolate Identification"],"prefix":"10.1111","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5894-2998","authenticated-orcid":false,"given":"Danielle","family":"Nolitt","sequence":"first","affiliation":[{"name":"Department of Small Animal Clinical Sciences UT College of Veterinary Medicine, University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7213-4759","authenticated-orcid":false,"given":"Elizabeth","family":"Drake","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences UT College of Veterinary Medicine, University of Tennessee  Knoxville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12665"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2007.00619.x"},{"key":"e_1_2_10_4_1","first-page":"1231","article-title":"Pseudomonas Otitis Externa in Dogs","volume":"59","author":"Pye C.","year":"2018","journal-title":"Canadian Veterinary Journal"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/inp.i1951"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2005.00465.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-018-1627-5"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-005-0151-x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12995"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-021-03066-7"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.13009"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2012.01075.x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12680"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40575-019-0075-2"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-020-2258-1"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40575-021-00106-1"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12040"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2009.00853.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myae053"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myy035"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2018.05.015"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12826"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.5326\/0400102"}],"container-title":["Veterinary Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/vde.13372","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T08:14:46Z","timestamp":1762416886000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/vde.13372"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,17]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.1111\/vde.13372"],"URL":"https:\/\/doi.org\/10.1111\/vde.13372","archive":["Portico"],"relation":{},"ISSN":["0959-4493","1365-3164"],"issn-type":[{"value":"0959-4493","type":"print"},{"value":"1365-3164","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,17]]},"assertion":[{"value":"2024-11-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}