{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:26:52Z","timestamp":1791473212900,"version":"4.3.4"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009231","name":"European Society of Veterinary Dermatology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009231","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Alopecia X (AX) is common in Pomeranians, and skin histological results support diagnosis. AX dogs may have shiny or woolly coats; the woolly type is implicated as a potential risk indicator.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare skin histological and trichographic results among Pomeranians with AX, and those unaffected by AX with woolly (W) and shiny (S) coat types.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Seventy\u2010two Pomeranians: 30 AX, 22 W, 20 S.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Materials<\/jats:title>\n                    <jats:p>Skin biopsies were analysed histologically; hair pluckings assessed by trichography and scanning electron microscopy (SEM), all blinded. Statistics evaluated follicular group counts, follicle numbers, hair types, anagen follicles and fragility events. Hair cycle staging was analysed descriptively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AX dogs had fewer follicles per group (4.1) than W and S (both 5.1). Anagen stage dominated in S (60.2%), telogen in W (39.4%) and AX (39.8%). Kenogen and atrophic groups were more frequent in AX (4.7% and 10.0%, respectively) than W (1.4% and 3.4%) and S (2.0% and 1.5%). Hair fragility per 10\u2009mg of hairs was highest in AX (85.3), followed by W (53.6) and S (26.3). Trichorrhexis nodosa ratios were for AX 12.39 (95% confidence interval [CI] 4.82\u201331.85) and W 3.60 (95% CI 1.37\u20139.94) compared to S. No differences in primary\u2010to\u2010secondary hair ratios were found between groups. SEM showed similar round hair morphology across groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Relevance<\/jats:title>\n                    <jats:p>Histological and trichographic findings in non\u2010alopecic Pomeranians reveal coat\u2010type differences, which should be considered when diagnosing AX.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vde.70054","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T11:21:53Z","timestamp":1771413713000},"page":"335-344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Histological and Trichographic Differences Between Coat Types in Non\u2010Alopecic Pomeranians and With Alopecia X"],"prefix":"10.1111","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-0197-9724","authenticated-orcid":false,"given":"Ilse","family":"van Hensbergen","sequence":"first","affiliation":[{"name":"IVC Evidensia Referral Hospital EDZ Arnhem  Arnhem the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4812-3216","authenticated-orcid":false,"given":"Chiara","family":"Brachelente","sequence":"additional","affiliation":[{"name":"Veterinary Pathology, Department of Veterinary Medicine, University of Perugia  Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0731-5801","authenticated-orcid":false,"given":"Jaco","family":"van der Lugt","sequence":"additional","affiliation":[{"name":"IDEXX B.V.  Hoofddorp the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"van den Broek","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences Theoretical Epidemiology, Faculty of Veterinary Medicine Utrecht University  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5173-2761","authenticated-orcid":false,"given":"Annette","family":"van der Lee","sequence":"additional","affiliation":[{"name":"IVC Evidensia Referral Hospital EDZ Arnhem  Arnhem the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,18]]},"reference":[{"key":"e_1_2_12_2_1","first-page":"501","volume-title":"Muller and Kirk's Small Animal Dermatology","author":"Miller W. 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