{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:11:25Z","timestamp":1789171885044,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Dermatology"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dermatophytes can be isolated from both symptomatic and asymptomatic cats, yet the role of skin commensals in modulating disease expression remains unclear. This study investigates whether microbial skin communities influence the clinical presentation (symptomatic or asymptomatic) of dermatophyte infection in Persian cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Hypothesis\/Objectives<\/jats:title>\n                    <jats:p>We hypothesised that the fungal and bacterial skin microbiota differ between Persian cats with and without clinical signs of dermatophytosis. The objectives of this study were to compare the fungal and bacterial skin microbiota among healthy, symptomatic, and asymptomatic cats with dermatophytosis and to evaluate the performance of two skin sampling methods (carpet and toothbrush) for microbiome analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>Forty\u2010five cats.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>\n                      Cats were grouped according to clinical presentation: Persian cats with skin lesions characteristic of dermatophytosis (multifocal alopecia and scaling) and a positive fungal culture (symptomatic group;\n                      <jats:italic>n\u2009=<\/jats:italic>\n                      \u200915), Persian cats with no skin lesions and a positive fungal culture (asymptomatic group;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200915), and domestic short hair cats with no history and clinical signs of skin disease and negative fungal culture (negative group;\n                      <jats:italic>n\u2009=<\/jats:italic>\n                      \u200915). Hair and scale samples were collected using carpet and toothbrush techniques from all animals. Fungal and bacterial communities were investigated using high\u2010throughput sequencing targeting internal transcribed spacer (ITS)1 and 16S ribosomal (r)RNA genes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Our data showed that the taxonomic composition of fungal and bacterial communities was similar between symptomatic and asymptomatic cats, regardless of the sampling method used. No notable differences were identified in the relative abundance of\n                      <jats:italic>Microsporum<\/jats:italic>\n                      spp. between symptomatic and asymptomatic cats.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions and Clinical Relevance<\/jats:title>\n                    <jats:p>Our findings suggest that the commensal microbiota may not influence the clinical presentation of dermatophyte infection. Instead, other factors, such as the host immune response, appear to play a pivotal role in determining disease outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vde.70058","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:12:46Z","timestamp":1773029566000},"page":"700-712","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Skin Commensal Microbiota Does Not Influence the Clinical Course of Dermatophyte Infection in Persian Cats"],"prefix":"10.1111","volume":"37","author":[{"given":"Aline E.","family":"Santana","sequence":"first","affiliation":[{"name":"Department of Internal Medicine School of Veterinary Medicine and Animal Science, University of S\u00e3o Paulo  S\u00e3o Paulo SP Brazil"},{"name":"Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila M. F.","family":"Torres","sequence":"additional","affiliation":[{"name":"Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota  Saint Paul Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9621-1977","authenticated-orcid":false,"given":"Matheus de O.","family":"Costa","sequence":"additional","affiliation":[{"name":"Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan  Saskatoon Saskatchewan Canada"},{"name":"Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University  Utrecht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12440"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjm.2015.11.027"},{"key":"e_1_2_10_4_1","first-page":"21","article-title":"Isolation of Dermatophytes From the Hair Coat of Healthy Persian Cats Without Skin Lesions From Commercial Catteries Located in S\u00e3o Paulo Metropolitan Area","volume":"44","author":"Nitta C. 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