{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T15:51:00Z","timestamp":1721577060988},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To describe the clinical presentation and case management of a dog that developed hemolytic anemia and evidence of renal tubular dysfunction after ingestion of a natural hair dye containing <jats:italic>Lawsonia inermis<\/jats:italic> (henna). To review cases of henna toxicity reported in the human literature.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Summary<\/jats:title><jats:p>An 8\u2010year\u2010old female spayed Border Collie was presented 5 days after ingestion of a box of natural hair dye. The dog was showing signs of lethargy, vomiting, diarrhea, and weakness. A serum biochemistry profile, complete blood count, and urinalysis demonstrated evidence of renal tubular dysfunction and a regenerative anemia without spherocytosis. The dog was treated with a transfusion of packed RBCs and IV fluids, resulting in significant clinical improvement. Repeat diagnostics showed resolution of the anemia and no lasting evidence of tubular dysfunction.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information Provided<\/jats:title><jats:p>To the authors\u2019 knowledge, this is the first reported case in the veterinary literature of toxicity following ingestion of <jats:italic>Lawsonia inermis<\/jats:italic> (henna). Henna ingestion was associated with the development of hemolytic anemia and acute kidney injury.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12113","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T22:05:21Z","timestamp":1383343521000},"page":"648-651","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hemolytic anemia after ingestion of the natural hair dye <i>Lawsonia inermis<\/i> (henna) in a dog"],"prefix":"10.1111","volume":"23","author":[{"given":"Daniel J.","family":"Jardes","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences Tufts University Cummings School of Veterinary Medicine  North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda A.","family":"Ross","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Tufts University Cummings School of Veterinary Medicine  North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica E.","family":"Markovich","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences Tufts University Cummings School of Veterinary Medicine  North Grafton MA 01536"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000139347"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2550110203"},{"issue":"1","key":"e_1_2_6_4_1","first-page":"65","article-title":"Henna\u2010induced hemolytic anemia and acute renal failure. 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