{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T15:23:38Z","timestamp":1791559418605,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T00:00:00Z","timestamp":1480896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Zoetis Animal Health"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare 2 treatment protocols (standard in\u2010hospital versus modified outpatient) in affecting the duration of treatment or survival of dogs with parvoviral enteritis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective, randomized study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>University teaching hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Animals<\/jats:title>\n                    <jats:p>\n                      Client\u2010owned dogs with naturally acquired parvovirus were randomized to receive either an inpatient (\n                      <jats:italic>n<\/jats:italic>\n                      = 20) or outpatient (\n                      <jats:italic>n<\/jats:italic>\n                      = 20) treatment protocol.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Both groups received intravenous (IV) fluid resuscitation and correction of hypoglycemia at hospital admission. Following stabilization, basic inpatient interventions included administration of IV fluids, administration of cefoxitin (22 mg\/kg IV q 8 h), and maropitant (1 mg\/kg IV q 24 h). Basic outpatient interventions (provided in\u2010hospital) included administration of subcutaneous (SC) fluid (30 mL\/kg q 6 h), administration of maropitant (1 mg\/kg SC q 24 h) and cefovecin (8 mg\/kg SC once). Using daily electrolyte and glucose evaluations, dextrose and potassium supplementation was provided intravenously (inpatients) or orally (outpatients) as indicated. Rescue criteria were used in both groups for analgesia and nausea. All dogs were syringe fed a commercial canine convalescence diet (1 mL\/kg PO q 6 h) until voluntary appetite returned.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements and Main Results<\/jats:title>\n                    <jats:p>\n                      Protocol success, defined as survival to hospital discharge, was 90% (18\/20) for the inpatient group compared to 80% (16\/20) for the outpatient group (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.66). There was no difference detected in duration of hospitalization for inpatient dogs (4.6 \u00b1 2 days) versus outpatient dogs (3.8 \u00b1 1.8 days,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.20). Metabolic disturbances were frequent in the outpatient group, with 50% of dogs requiring dextrose supplementation and 60% of dogs requiring potassium supplementation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>An outpatient protocol may be a reasonable alternative for dogs that cannot receive standard in\u2010hospital treatment for parvoviral enteritis. Diligent supportive care and monitoring are still required to optimize treatment of dogs with parvoviral enteritis in an outpatient setting.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/vec.12561","type":"journal-article","created":{"date-parts":[[2016,12,5]],"date-time":"2016-12-05T10:42:59Z","timestamp":1480934579000},"page":"52-65","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Evaluation of an outpatient protocol in the treatment of canine parvoviral enteritis"],"prefix":"10.1111","volume":"27","author":[{"given":"Emilee C.","family":"Venn","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences Colorado State University Fort Collins CO 80523"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Preisner","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, 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