{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T03:11:32Z","timestamp":1788577892687,"version":"build-2803163510"},"reference-count":66,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,8,3]],"date-time":"2018-08-03T00:00:00Z","timestamp":1533254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"ACVIM Cardiology Resident Research Grant","award":["Awarded 2013"],"award-info":[{"award-number":["Awarded 2013"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To assess distribution of alveolar\u2010interstitial syndrome (AIS) detected by lung ultrasound (LUS) compared to thoracic radiographs (TXR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Prospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>University teaching hospital.<\/jats:p><\/jats:sec><jats:sec><jats:title>Animals<\/jats:title><jats:p>Seventy\u2010six dogs and 24 cats with acute respiratory distress or tachypnea.<\/jats:p><\/jats:sec><jats:sec><jats:title>Interventions<\/jats:title><jats:p>Patients underwent LUS and TXR within 6 hours. Lung ultrasound images were scored for presence and quantity of B\u2010lines in 4 lung quadrants (right cranial, right caudal, left cranial, left caudal). An individual LUS quadrant was scored positive if &gt; 3 B\u2010lines were observed within a single intercostal space. Dorsoventral TXR were scored for presence of AIS in the same 4 quadrants. An individual TXR quadrant was scored positive if infiltrate was present in \u2265 25% of the quadrant. Medical records were evaluated for final diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements and Main Results<\/jats:title><jats:p>Quadrant\u2010by\u2010quadrant spatial agreement in assigning AIS using LUS versus TXR was fair (<jats:italic>K<\/jats:italic>\u00a0=\u00a00.24 \u2013 0.56). Lung ultrasound scored a higher number of quadrants positive per patient (2.65\u00a0\u00b1\u00a01.59 vs. 2.13\u00a0\u00b1\u00a01.48;<jats:italic>P<\/jats:italic>\u00a0=\u00a00.012). Patterns of distribution of AIS differed significantly based on final diagnosis. Patients with left\u2010sided congestive heart failure were more likely to have diffuse AIS on LUS (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) or bilateral caudal AIS on TXR (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.04) while patients with noncardiac disease were more likely to have absence of AIS in all quadrants using either modality (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Differences in spatial distribution of AIS were also noted among disease subcategories.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Lung ultrasound and TXR were both useful to detect and categorize distribution of alveolar or interstitial pulmonary pathology. Spatial agreement between modalities was only fair. Overall, LUS detected a higher incidence of AIS compared to TXR. Both modalities detected differences in distribution of AIS based on final diagnosis, suggesting that a regional pattern\u2010based approach to thoracic imaging may prove diagnostically useful.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12750","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T05:49:15Z","timestamp":1533620955000},"page":"415-428","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Distribution of alveolar\u2010interstitial syndrome in dogs and cats with respiratory distress as assessed by lung ultrasound versus thoracic radiographs"],"prefix":"10.1111","volume":"28","author":[{"given":"Jessica L.","family":"Ward","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences, College of Veterinary Medicine Iowa State University Ames IA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory 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