{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:26:49Z","timestamp":1790713609901,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T00:00:00Z","timestamp":1556755200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Vet Emergen Crit Care"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To describe the successful management of 2 dogs with septic shock and persistent tachycardia using norepinephrine and esmolol, a short\u2010acting beta receptor antagonist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Series Summary<\/jats:title><jats:p>Two cases are reviewed. In the first case, septic shock with ventricular tachycardia was diagnosed in a 4\u2010year\u2010old neutered female Great Dane that underwent jejunoileal resection and anastomosis for a partial mesenteric torsion. The patient's tachyarrhythmias failed to respond to lidocaine, and an esmolol infusion was used for heart rate control. The condition of the dog improved and she was discharged after 4 days of hospitalization. The second case was a 7\u2010year\u2010old neutered female Cavalier King Charles Spaniel with septic peritonitis. Following surgery for intestinal resection and anastomosis, supraventricular tachycardia developed that was not responsive to volume resuscitation and was treated with an esmolol infusion. The condition of the dog improved and she was discharged after 6 days of hospitalization. Both patients were doing well at the time of long\u2010term follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>New or Unique Information Provided<\/jats:title><jats:p>This case series highlights a novel method of managing dogs in septic shock with persistent tachycardia based on recently published data in the human literature. The use of esmolol may be considered in certain veterinary patients with septic shock to improve persistent tachycardia not related to hypovolemia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/vec.12830","type":"journal-article","created":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T07:25:57Z","timestamp":1556781957000},"page":"326-330","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Successful management of persistent tachycardia using esmolol in 2 dogs with septic shock"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9867-0357","authenticated-orcid":false,"given":"Kari Santoro","family":"Beer","sequence":"first","affiliation":[{"name":"Matthew J. Ryan Veterinary Hospital University of Pennsylvania  Philadelphia PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusha","family":"Balakrishnan","sequence":"additional","affiliation":[{"name":"The Ohio State University College of Veterinary Medicine  Columbus OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha K.","family":"Hart","sequence":"additional","affiliation":[{"name":"Matthew J. 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